Head Portfolio Strategy & Operations Neuroscience & Gene Therapy

Novartis Gene Therapies
Cambridge, MA
Summary

Onsite

Cambridge, MA

East Hanover, NJ

About The Role

As Head of Portfolio Strategy & Operations, Neuroscience and Gene therapies (NS & GTx), you will lead the therapeutic area and portfolio strategy. You will serve as a thought partner for the NS & GTx Head and leadership team, in collaboration with key stakeholders along the R-D-C continuum, while considering internal & external factors impacting the neuroscience and gene therapies portfolio. You will have the opportunity to lead the team’s operations and oversee program execution by actively partnering with Global Program Heads, development line functions, global medical affairs, and other key stakeholders, while partnering directly with the Global Program Manager function with workforce planning, demand planning, & resource needs in NS & GTx. You may also deputize for the NS & GTx Head. This position reports to the DU Head.

About The Role

Your Key Responsibilities:

  • Serve as a thought partner for the NS & GTx unit head and leadership team on all topics related to strategy, portfolio strategy and program-level strategic considerations.
  • Lead the strategic initiatives within NS GTx and contribute to development or enterprise-level initiatives.
  • Co-lead the NS & GTx strategy review in collaboration with the NS & Gtx Head and other NS & GTx members; works in collaboration with NS & GTx leadership members and their respective organizations; prepares outputs for Novartis senior management, Board of Directors and external audiences (e.g., investors).
  • Proactively monitor external landscape (incl. industry, regulatory landscape etc.), assesses impact on portfolio and derives concrete actions / recommendations.
  • Lead governance, effective discussion and quality decision making at NS & GTx Leadership team; Point person for portfolio & strategy related activities and requests .
  • Lead effective internal and external communication to include IR and pipeline communications via generation or review of all NS & GTx level reports; lead development of strategic communication and associate engagement plan.
  • Translate NS & GTx strategy into NS & GTx leadership team and development leadership team objectives jointly with GPTs and DU LFs; continuously tracks status.
  • Optimize the portfolio value and update relevant NS & GTx strategy.
  • Prepare (and support leadership team in preparation) for governance meetings, including in-writing memos and monthly updates. Liaising with governance boards to coordinate flow of review.
  • May manage the NS & GTx Operational Manager(s) and have direct reports ranging from 1-5 associates.
  • Accountable for external annual DU budget Planning and management of department headcount (10-20 FTEs) and oversight of the DU project development costs.
  • Ensures resource optimization through influencing trial and program design by matching investment to portfolio prioritization and risk profile.

Video Link

This position will be located at the Cambridge, MA or East Hanover, NJ site and will not have the ability to be located remotely. This position will require 5% travel as defined by the business (domestic and/ or international).

Role Requirements

Essential Requirements:

  • Master’s degree or equivalent education/degree in life sciences or healthcare and 10+ years of drug development experience, and knowledge of drug development strategy.
  • 5+ years people and matrix management experience.
  • Excellent problem-solving, negotiation and conflict resolution skills.
  • Considerable organizational awareness, including significant experience working cross-functionally and in global teams.
  • Strong relationship builder and communicator with experience leading diverse work teams, driving program excellence, engaging functional partners, and partnering with disease unit Head and Business Franchise Head.
  • Advanced planning and project management skills, with understanding of business processes.

Desired Requirements

  • MD, PhD or MBA highly desired.
  • Global people management experience

Novartis Compensation And Benefit Summary

The salary for this position is expected to range between $225,400 and $418,600 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis

Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here:

You’ll Receive

You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.

Read our handbook (PDF 30 MB)

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Posted 2026-02-21

Recommended Jobs

Seasonal Winter Area Manager

JC Grounds Management
Framingham, MA

Join a dedicated team committed to delivering high-quality winter services as a Seasonal Winter Area Manager. In this dynamic, hands-on role, you will oversee operational staff and service partners d…

View Details
Posted 2026-02-04

Training and Development Specialist

Sevita
Worcester, MA

Mentor South Bay, provides Early Intervention, Applied Behavioral Analysis (ABA), Behavioral Health and Mental Health Outpatient services across Massachusetts and Connecticut. For over 35 years, we’v…

View Details
Posted 2026-02-07

Virtual Sales Insurance Specialist (Boston)

Globe Life: The Gelb Group
Boston, MA

Remote Sales Insurance Specialist Are you enthusiastic, self-motivated, and eager to learn? Do you thrive in a fast-paced environment and aren't afraid of hard work? If so, we want to hear from yo…

View Details
Posted 2026-02-22

Electrical Service Technician

Rodenhiser Home Services Inc
Holliston, MA

Rodenhiser has been crafting an elite team of technicians since 1928 who service thousands of happy customers.  With Rodenhiser’s size comes numerous advantages you won’t find elsewhere. At Rodenh…

View Details
Posted 2026-01-26

Psychiatric Nurse Practitioner- Mental Health

Lifebulb
Waltham, MA

Job description At risk of being a bit blunt, we founded Lifebulb because we're tired of therapists being treated like numbers on a company's financial spreadsheet. You're a person. And your clien…

View Details
Posted 2025-12-31

Travel CT Tech Job - $3,021 per Week (2 Years Experience Needed)

Golisano Children's Hospital of Southwest Florida
Lowell, MA

We are seeking a dedicated Travel CT Tech in Lowell, MA, offering $3,021/week. This role involves performing high-quality computed tomography scans, ensuring patient safety, and maintaining equipment …

View Details
Posted 2026-01-25

Associate Project Manager, Construction

WS Development
Chestnut Hill, MA

Overview WS Development is seeking a driven and detail-oriented Associate Project Manager to support our Construction team as we deliver new core-and-shell, ground-up construction projects across …

View Details
Posted 2026-02-14

Security Service Technician

Johnson Controls
Massachusetts

We hope you will join our diverse team of top people you bring your talent, and we’ll give you the space and opportunities to grow and succeed.  We are committed to make a difference. What we offe…

View Details
Posted 2026-02-02

Service Technician - The 6Hundred

Greystar
Worcester, MA

ABOUT GREYSTAR Greystar is a leading, fully integrated global real estate platform offering expertise in property management, investment management, development, and construction services in ins…

View Details
Posted 2026-02-19

Grants Manager

JVS Boston
Boston, MA

POSITION: Grants Manager FLSA: Exempt Status: Full-Time REPORTS TO: Associate Director, Advancement & Donor Engagement Location: Boston, MA This is a hybrid position, and the candida…

View Details
Posted 2025-08-12