Principal Scientist, Kidney Disease Research Expert - In Vitro, CVRI
Bayer has an opening for a Principal Scientist to join our Cardiovascular-Renal In Vitro Research group based at the Bayer Innovation Campus at the heart of Kendall Square in Cambridge, MA, to further strengthen our experience in the kidney disease space globally and help build up a team of researchers at this site.
We are looking for an expert scientist with deep knowledge of Kidney Disease Biology and demonstrated experience with the discovery and development of therapeutics. This is an excellent opportunity for a highly motivated candidate interested in driving and growing our therapeutics pipeline in a vibrant and collaborative atmosphere. Your Tasks And Responsibilities The primary responsibilities of the Principal Scientist, CVRI (Cardiovascular, Renal & Immunology), Complex In Vitro sub-cluster–Principal Scientist are to:- In preclinical programs, act as disease biology lead ensuring excellence in kidney biology sounding as well as alignment and timely delivery of pharmacology related deliveries to efficiently advance programs towards milestones and go/no go decisions, including concise and regular presentation of program results to senior stakeholders.
- Support and contribute to the drug development strategy of CVRI, with particular focus on kidney diseases and the intersection of the cardiovascular, renal, metabolic space.
- Design and supervise the execution of functional cellular disease models to support target identification, therapeutic candidate characterization, and mechanism of action evaluations.
- Provide scientific leadership and seek innovative solutions (internally and externally) in the application of in vitro methods to support our early discovery pipeline.
- Contribute key documentation and presentations for projects moving through internal review stage gates and regulatory submissions.
- Support the management and coaching of research associates and junior scientists in a matrix organization.
- Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators.
- Assess external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration or technological innovation.
- Maintain and extend a network with external partners from academia, contract research organizations and medical experts.
- Foster creativity and motivation between scientists.
Bayer seeks an incumbent who possesses the following:
Required qualifications:- A Ph.D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field.
- A strong background in kidney disease biology is essential, and further expertise in cardiovascular or metabolic space would be highly advantageous.
- Demonstrated track record in the drug discovery process in a pharmaceutical or biotech setting would be highly advantageous.
- A deep knowledge and hands-on experience in designing and establishing translatable functional cellular disease models (2D or 3D) to aid target identification and therapeutic evaluation.
- Deep expertise in the application of state-of-the-art in vitro methods across the early drug discovery process (including molecular biology, biochemistry, and cellular analytical techniques).
- Experience in the design and execution of early-stage research program(s) to identify and validate novel targets
- Excellent verbal and written communication and interpersonal skills to work across functions and within external collaborations, and a demonstrated ability to organize and communicate complex data sets in a clear and concise manner to cross-functional audiences
- Ability to adapt to and effectively manage changes in a fast paced and dynamic environment
- A passion for science and sense of urgency to find new medicines to benefit patients
- 8+ years of relevant post-PhD experience including 4+ years in industry is preferred, with a proven record of successful team leadership and interaction with collaborators
Employees can expect to be paid a salary between $136,000.00 $204,000.00. Additional compensation may include a bonus or commission (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.
This salary range is merely an estimate and may vary based on an applicant’s location, market data/ranges, an applicant’s skills and prior relevant experience, certain degrees and certifications, and other relevant factors. This posting will be available for application until at least 03/12/2026 YOUR APPLICATION Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Health for all, Hunger for none, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer. To all recruitment agencies: Bayer does not accept unsolicited third party resumes. Bayer is an Equal Opportunity Employer/Disabled/Veterans Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. Equal Opportunity Employer Statement: Notice for U.S. Visitors: All information on this site is subject to compliance with local rule and regulations as they may vary from time to time and across different geographies, including, without limitation, U.S. Executive Orders. Bayer is an E-Verify Employer. Location: United States : Massachusetts : Cambridge Division: Pharmaceuticals Reference Code: 862466 Contact Us Email: [email protected]Recommended Jobs
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