Research Associate, Next Generation Sequencing (NGS) and Genomics

Cystic Fibrosis Foundation
Lexington, MA

The Cystic Fibrosis Foundation is a leading healthcare nonprofit organization like no other. For decades, we have been taking major steps and pioneering new ways to advance the mission to find a cure for cystic fibrosis and to provide all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, partnering with the CF community, and advancing high-quality, specialized care.


By joining the Cystic Fibrosis Foundation
, you will be part of a dedicated team committed to our core values and working towards a cure for cystic fibrosis. We offer a collaborative and supportive work environment, opportunities for professional growth, and the chance to make a meaningful impact in the lives of those affected by CF. Learn more about why work at the Cystic Fibrosis Foundation.

Position Summary:

The Research Associate, Next Generation Sequencing (NGS) and Genomics will conduct laboratory functions under general supervision of the Head of NGS and Genomics. She/He will work as part of a team in the operation of the Next Generation Sequencing (NGS) and Genomics laboratory to achieve departmental goals. Responsibilities include hands-on preparation of NGS libraries, operation, and maintenance of NGS instrumentation including Single Cell, Next Generation, and Third Generation sequencing platforms. Strong ability to troubleshoot routine as well as novel NGS essays such as target enrichment methods, assays to quantify on-and off-target genome editing, ChIP-Seq, ATAC-seq, and other methods to explore chromatin biology.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Nucleic acid extraction and QC.

  • Manipulation of DNA (PCR, Electrophoresis, etc.).

  • NGS library preparation.

  • Operation and maintenance of NGS instrumentation.

  • Troubleshooting and Quality Control of library construction and sequencing runs.

  • Participate in group meetings for discussion of data and suggested next steps.

  • Maintain detailed records of the work carried out (electronic lab notebook).

  • Prepare and present results at internal meetings.

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

  • B.S./M.S. in Life Sciences with up to four years R+D laboratory experience.

  • Good attention to detail.

  • Good communication, collaboration, problem solving skills.

  • Detail-oriented and capable of multi-tasking in a dynamic team.

REPORTING RELATIONSHIPS:

  • Reports to the Scientist IV. No direct reports.

WORKING CONDITIONS:

  • Commute to lab every workday.

  • Research Lab with chemical and biological hazards present.

  • Must have access to reliable transportation.

  • Use of computer required.

  • Must be able to work from home when road conditions do not permit travel to workplace.

  • Sitting, bending, reaching, and walking.

The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of essential functions, responsibilities, or requirements.

This position will be posted for a minimum of 5 days or until the position is filled. Applications will be accepted on an ongoing basis, so candidates are encouraged to apply promptly if interested.

The salary range is $71,600.00 to $89,500.00. Specific salary varies based on geographic location and is commensurate with experience.

Total Rewards: The CF Foundation is committed to offering competitive compensation (base pay and incentive), benefits, time off and professional development opportunities that maximize our ability to recruit, retain, reward, and motivate a highly qualified and diverse workforce. Visit our Why Work at the Cystic Fibrosis Foundation for detailed total rewards information.

The CF Foundation is an equal opportunity employer that is committed to being an employer of choice, not just a good place to work, but a great and inclusive place to work. We strive to recruit and maintain a diverse workforce. Qualified applicants will receive consideration for employment without regard to race, physical or mental disability, color, religious creed, ancestry, national origin, religion, age, sex, pregnancy, marital status, genetic information or testing, gender identity and expression, sexual orientation or status as a Vietnam-era or special disabled veteran or any characteristic protected by law.

Reasonable Accommodations: The CF Foundation is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or would like to request an accommodation due to a disability, please contact us at [email protected].

Posted 2026-04-11

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