Senior Scientist, In Vivo Pharmacology, Oncology
- Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)
- Paid time off policy including holidays and sick time
- Internal growth and development programs & trainings
- 401(k) program, life & accident insurance and disability insurance
- Manage a team of 4-6 junior staff members, ensuring effective coordination and task execution
- Track study timelines, deliverables, and maintain high standards of data quality and documentation.
- Provide mentorship and technical guidance to lab leads and junior scientists.
- Oversee training programs for new hires and refresher training for existing staff.
- Serve as the first point of contact for complex staff questions and performance concerns.
- Conduct regular 1:1s, performance reviews, and development check-ins.
- Lead onboarding and integration of new team members.
- Manage cell culture lab to include; care and maintenance of equipment and space.
- Skilled in cell culture, inoculation, aseptic technique and contamination prevention.
- Participate in protocol development and review with Discovery Research and cross-functional teams.
- Coordinate study scheduling and establish timelines of delivery of cells for inoculation.
- Execute dosing and surgical procedures, including tumor induction (xenograft models), IV, IP, SC, IM, PO administrations, perfusion, tissue resection, microdissection, biological sampling, survival surgery, and necropsy.
- May assist in image acquisition (PET, SPECT, CT, MRI and BLI) and related procedures.
- Handle radioactive and BSL2 materials, including sample processing, gamma counting, and proper waste disposal.
- Ensure strict adherence to laboratory SOPs and regulatory guidelines (IACUC, radiation safety, lab safety).
- Monitor and report on animal health in collaboration with attending veterinarian.
- Present study data to internal teams and sponsors.
- Prepare reports, slide decks, and summaries for senior leadership.
- Support regulatory and QA/QC inspections; ensure team readiness and documentation accuracy.
- Identify workflow inefficiencies and implement process enhancements (e.g., SOPs, automation tools).
- Contribute to strategic planning by evaluating and integrating new models and methodologies.
- Hands-on experience with building in vivo oncology models, which could include subcutaneous xenograft, patient-derived xenograft (PDX), syngeneic, or humanized mouse models
- Expertise in standard in vivo techniques (IV dosing, surgical procedures, biological sampling).
- Demonstrated experience in handling small animals, especially for oncology studies
- Microdissection of specific tissues (e.g., lymph nodes, brain sections)
- Ability to manage multiple projects and prioritize effectively.
- Bachelor's degree in Biology, Animal Science, or related field with 15+ years of relevant in vivo research experience or advanced degree with 10+ years of relevant in vivo research experience.
- Demonstrated experience managing or mentoring laboratory staff.
- Excellent multitasking, organizational, and time-management skills.
- Strong written and verbal communication abilities.
- Competence with computer systems and laboratory data platforms.
- Ability to lift up to 50 pounds.
- Standard working hours are Monday through Friday, 9 AM - 5 PM, with occasional weekend work as required.
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