Director, In vivo Expert, CVRI (Cardiovascular, Renal & Immunology)
- Design, supervise and lead the execution of rodent in vivo mechanistic and disease models to support target identification, therapeutic candidate characterization, and mechanism of action evaluations utilizing internal and external resources (CROs) efficiently;
- Responsible for leading multiple drug discovery programs, initiatives, or external collaborations in Research / Early Development (RED) CVRI from target identification through support of early clinical development;
- Works as an expert opinion in Target ID teams or early research teams, providing disease-biology and in vivo model expertise to identify and advance projects within the global Bayer strategic frames;
- In preclinical programs, act as disease biology lead ensuring excellence in biology sounding as well as alignment and timely delivery of pharmacology related deliveries to efficiently advance programs towards milestones and go/no go decisions, including concise and regular presentation of program results to senior stakeholders;
- Support and contribute to the strategic development of the capability cluster “In Vivo”, demonstrating scientific leadership and seeking innovative solutions (internally and externally) in the application of in vivo models to support our discovery pipeline;
- Support and contribute to the drug development strategy of CVRI, with particular focus on cardio-renal diseases, as well as the intersection of the cardiovascular, renal, and metabolic space;
- Collaborate with other R&D functions and support cross team and cross site activities;
- Contribute key documentation and presentations for projects moving through internal review stage gates and regulatory submissions;
- Employing VACC (Visionary, Architect, Coach, Catalyst) leadership principles to support management and coaching of research associates and junior scientists in a global matrix organization;
- Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators;
- Assess external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration, in-licensing or technological innovation;
- Maintain and extend a network with external partners from academia, contract research organizations and medical experts, with particular emphasis on the local Boston landscape;
- Foster creativity and motivation between scientists;
- Ensure that all tasks are aligned with respect to HSE guidelines, animal welfare law, documentation, and good research practices.
- Ph.D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field is required;
- Strong background in cardio-renal is essential, and further expertise in cardiovascular or metabolic space would be highly advantageous;
- Demonstrated track record in the drug discovery process in a pharmaceutical or biotech setting;
- A deep knowledge and hands-on experience in designing and establishing translatable in vivo rodent disease models to aid target identification and therapeutic evaluation;
- Deep expertise in the application of state-of-the-art in vivo models across the drug discovery process (including rodent mechanistic and disease models with clinically relevant read-outs and endpoints);
- Experience in the design and execution of early-stage research program(s) to identify and validate novel targets;
- Experience in strategic planning and project leadership.
- 12+ years of relevant post-PhD experience including 4+ years in industry is preferred, with a proven record of successful drug discovery team leadership and interaction with collaborators.
YOUR APPLICATION
Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Health for all, Hunger for none, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Equal Opportunity Employer Statement: Notice for U.S. Visitors: All information on this site is subject to compliance with local rule and regulations as they may vary from time to time and across different geographies, including, without limitation, U.S. Executive Orders. Bayer is an E-Verify Employer. Location: United States : Massachusetts : Cambridge || United States : Massachusetts : Boston Division: Pharmaceuticals Reference Code: 873535 Contact Us Email: [email protected]
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