Senior Scientist - Immunotherapy

Work Location: Billerica, Massachusetts
Shift: No
Department: HC-RD-TM3D Tumor Immunology 3D
Recruiter: Beverly Dellisola

This information is for internals only. Please do not share outside of the organization.

Your Role:

Help shape the next generation of cancer immunotherapies at EMD Serono in Billerica, MA. As an in vitro Senior Scientist, you will not only execute experiments but also lead and represent the in vitro strategy on discovery teams working on Tumor Immunology projects. Our goal is to mobilize adaptive and innate immunity-spanning antibody therapeutics, T-cell engagers, checkpoint modulators, and myeloid/NK activators-turning bold ideas into high-quality clinical candidates in a fast-paced, highly collaborative environment.

Responsibilities:

• Design and execute in vitro/ex vivo human immune tumor co-culture assays; profile function via flow cytometry, cytokine/biomarker readouts, and high-content imaging.

• Build and validate human immunology models that complement animal studies to improve translational predictivity and de-risk candidates.
• Scout, implement, and champion new assay platforms to investigate novel MOAs, boost data quality, throughput, and decision-making speed.
• Independently generate in vitro data for target selection, lead optimization, candidate nomination; and enable program decisions toward IND-enabling studies.
• Analyze, document, and present results to multidisciplinary teams and senior leadership; manage CROs and academic collaborations where needed.
• Provide creative, strategic input-conceive new project ideas and help design execution-ready workplans.

Who You Are:

Minimum Qualifications:

• Master's degree in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 5+ years of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting
• PhD in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 2+ years post-PhD of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting

Preferred Qualifications:

• Expertise developing, running complex T-cell functional assays (activation receptors, costimulatory molecules, checkpoint receptors) and interpreting mechanistic data to inform early development. Hands on experience with T-cell engagers and (ADCs).
• Experience in designing, executing, and interpreting in vitro assays for drug discovery, including tumor models and pharmacology experiments
• Clear, crisp communicator; highly organized multitasker who adapts quickly to deliver on-time data packages
• Confident influencer who engages senior leadership and thrives in a matrixed organization
• Proven scientific impact-publications and contributions advancing new therapeutic concepts

Pay Range for this position: $83,500 - $138,500

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here .

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