Manager, Stock Plan Administration

Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Opportunity Overview
As the Manager, Stock Plan Administration, you will be responsible for overseeing and expanding Rhythm’s public company equity program, while maintaining high standards of operational efficiency, regulatory compliance, and employee engagement. You will be a key member of the People Operations team, responsible for the full lifecycle of equity administration, from grant issuance to compliance, employee education, liquidity events, and audits. You will collaborate cross-functionally and drive process improvements to support our growing organization.

Responsibilities and Duties

• Responsible for administration of Rhythm’s global equity programs, including public RSUs and stock options: oversee grant issuance, tracking, vesting, exercises, cancellations, deferred releases, and liquidity events, ensuring accuracy, compliance, and timeliness.
• Serve as primary administrator for the equity management platform (e.g., E*Trade), maintaining records, updating grant agreements, and managing system audits.
• Oversee global equity administration, ensuring compliance with international regulations and supporting employees in multiple countries.
• Serve as initial point of contact for employee equity questions across multiple countries, building and delivering applicable informative documentation and internal trainings.
• Drive periodic equity refresh cycles and new hire grant programs, including modeling, planning, and execution in alignment with company guidelines.
• Partner with Total Rewards and HR Business Partners to deliver clear communications and education on equity topics; respond to employee inquiries with professionalism and clarity.
• Ensure compliance with internal policies and external regulations (SEC, IRS, ISO/NSO rules), engaging outside counsel as needed.
• Collaborate with Legal, Finance, HR, and external advisors to align on equity-related matters and support strategic initiatives.
• Identify and implement process improvements to streamline, document, and scale equity operations in a dynamic, high-growth environment.
• Support audits, modeling, and board reporting related to equity compensation.
• Facilitate onboarding/offboarding equity processes and coordinate with HRIS and Payroll.

Qualifications and Skills

• Minimum 5 years of experience in equity administration, ideally within a public company.
• Deep understanding of equity types (ISOs, RSUs) and related tax and compliance considerations.
• Proficiency with equity platforms such as E*Trade.
• Excellent attention to detail, organizational skills, and ability to manage multiple priorities in a fast-paced environment.
• Strong communication skills with the ability to explain complex equity concepts to diverse stakeholders.
• Experience with French qualified equity programs a plus.
• Familiarity with deferred compensation, 409A, and public company equity best practices preferred.
• CEP Level I certification is a plus.
• Ability to handle sensitive information with discretion and confidentiality.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.


The expected salary range for this position is $110,000 - $165,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.

More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.

At Rhythm our core values are:

• We are committed to advancing scientific understanding to improve patients' lives
• We are inspired to tackle tough challenges and have the courage to ask bold questions
• We are eager to learn and adapt
• We believe collaboration and ownership are foundational for our success
• We value the unique contribution each individual brings to furthering our mission

Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.

Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.