Postdoctoral Fellow

Job Description

Job Description

Description:

The ADA Forsyth Institute was founded in 1910 as the Forsyth Dental Infirmary for Children (later, the Forsyth Institute), to provide dental care to the disadvantaged children of Boston. While continuing to serve children in need, yet recognizing the ultimate goal is to prevent dental disease, the Institute in 1915 began to focus on scientific research and is today the world’s leader in oral health research. In October of 2023, the Institute joined with the American Dental Association to form the ADA Forsyth Institute, a 501(c)(3) entity dedicated to improving people’s oral and overall health and powering the profession of dentistry through cutting-edge basic research, creative translational science, innovative clinical technologies, and global public health outreach. Consistent with the Institute’s founding mission, the ADA ForsythKids mobile dental program continues to serve children in need.

The Chengji Zhou lab recently relocated from University of California to the ADA Forsyth Institute, has an immediate opening for a Postdoctoral Fellow to study the mechanism and prevention of tissue closure birth defects, including neural tube defects and orofacial clefts, both projects have been funded by NIH. The Zhou lab utilizes molecular, cellular, embryological, genetic, and single-cell genomic approaches to address the mechanisms underlying tissue closure and related birth defects in genetically modified mutant mouse models.

Basic Qualifications

• Recent Ph.D. or equivalent in biomedical fields
• 2-4 years of wet-lab research experience with expertise in a specific field demonstrated by publication
• Highly motivated and responsible
• Excellent analytical, problem solving, and experimental skills
• Good interpersonal and communication skills
• Willing to work in a collaborative environment

Preferred Skills and Responsibilities

• Hands-on experience with mouse works, including colony management, sample collection, and PCR genotyping
• Sample embedding and sectioning using a cryostat
• Immunohistochemistry and western blot
• RNA probe preparation, section and wholemount in situ hybridization, RNAscope, and related microscopic imaging technologies
• RNA extraction and real time RT-PCR
• Chromatin immunoprecipitation and promoter luciferase assay
• Bioinformatics in sequencing and single-cell genomic analyses is a plus

To Apply

Interested candidates are encouraged to submit their application, including a curriculum vitae, and the name and contact information of 3 references. Questions can be directed to Dr. Chengji Zhou at [email protected].