Research Scientist

Job Title : Research Scientist
Location: Cambridge, MA (Onsite role)
Duration: 18 months
Pay Rate: ***/hour - ***/hour
Our Global Genetically Engineered Models (GEMs) Team within Comparative Medicine (CM) supports the expansion of animal science, preclinical care, and research model development furthering research across the world. We are the innovation incubator within in vivo pre-clinical research and are the central partner for in vivo scientific input, organizing and performing all in vivo activities.


The role is a highly technical and/or specialized professional position responsible for supporting several disease areas across *** Biomedical Research (Cambridge, MA USA) providing high quality & consistent in vivo technical research support within our multi-building, multi-discipline research program. The role is primarily lab-based and on-site.
Job Purpose:
To conduct genotyping analysis of genetically modified mouse lines housed in our breeding facility. Project-based support of initial genetic characterization of newly generated and breeding mouse lines, thus contributing to in vivo research in various research areas within BR.
Your key responsibilities will include, but are not limited to:
Plan and execute genotyping experiments for genetically modified mice in accordance with established protocols.
Perform genetic characterization of newly generated and breeding mouse lines.
Support the development, implementation, and optimization of new methods for genetic characterization.
Ensure accurate documentation, analysis, and reporting of experimental data.
Maintain laboratory operations, including organization, equipment upkeep, and ordering of consumables.
Contribute to the overall success of the GEMs team by delivering high-quality in vitro and in vivo work and providing flexible support across team activities as needed.
What you'll bring to the role:
Bachelor's degree in Biological Sciences (e.g., Genetics, Developmental Biology, Molecular Biology, or a related discipline) with 1-2 years of relevant hands-on laboratory experience.
Molecular Biology Expertise
Demonstrated experience designing and optimizing PCR-based assays for accurate and unambiguous determination of mouse genotypes.
Hands-on experience with qPCR methodologies (SYBR Green, TaqMan, and/or ddPCR); familiarity with NGS library preparation is an advantage.
Mouse Model and Genetics Knowledge
Solid working knowledge of mouse model systems, transgene structures, and genetic strategies (e.g., inducible knockout models), as well as Mendelian genetics.
Foundational understanding of transgenic and knockout mouse generation processes to support genetic characterization of newly generated or imported lines.
Operational and Logistics Experience
Experience with laboratory ordering processes and logistics, including procurement of consumables through e-Shop or comparable systems.
Desirable:
Innovation: Demonstrates a willingness to stay current with scientific and technological developments and actively challenges existing processes to achieve high-quality results.
Quality: Shows a strong sense of responsibility and commitment to delivering high-quality outcomes, with the ability to remain focused and precise during repetitive tasks.
Collaboration: Exhibits a proactive, professional, and respectful approach toward colleagues and collaborators. Communicates effectively building strong working relationships and demonstrates a clear understanding of the importance and impact of working in a service-oriented laboratory environment.
Performance: Displays a high level of motivation and a strong interest in understanding the underlying science to support effective collaboration with project teams and implementation of new technologies. Works independently while maintaining flexibility and a strong team-oriented mindset.
Courage & Integrity: Demonstrates accountability for personal actions and a sense of responsibility for contributing to the success of the unit within ***. Addresses issues openly, constructively, and without hesitation.