Part-Time Bioinformatics NGS Data Analyst Consultant (LC 34576-1)

Job Description

Job Description

PT work:

Desired Start Date: 6/30/2025
End Date: 12/31/2025

Hrs/Wk:20.00 (negotiable)

Work enviroment: Hybrid at Cambridge, MA

POSITION SUMMARY:
• The project focuses on the assay development of next-generation sequencing (NGS)-based viral detection.
• The role will transform existing bash and Python analysis programs into efficient Nextflow workflows.
• The successful candidate will have a proven track record in bioinformatics and Nextflow workflow development utilizing high-throughput sequencing data.
• They are expected to be detail-oriented, capable of working independently, and able to collaborate with project management and collaborators.
• Maintain detailed documentation of workflow processes and provide regular updates on project progress.

POSITION RESPONSIBILITIES:
• Develop and implement Nextflow workflows based on an existing analysis workflow to streamline our NGS-based viral detection processes.
• Translate existing analysis programs, initially developed in bash and python, into modular Nextflow workflows.
• Provide insights and recommendations for improvements in workflow design and tool utilization.
• Demonstrate strong understanding of bioinformatics tools and their application to NGS data analysis.
• Utilize tools, such as BLAST, STAR, Bowtie, samtools, and Python-based packages to optimize workflow performance and accuracy in the viral detection assay.
• Maintain comprehensive documentation of workflows on GitHub for reproducibility.
• Regular report on progress, challenges, and outcome to project management and collaborators.

ORGANIZATIONAL RELATIONSHIPS:
• Machine Learning and Computational Sciences (MLCS) group at Company
• Biotherapeutic Pharmaceutical Sciences (BTx Pharm Sci) group at Company

EDUCATION AND EXPERIENCE:
• Bachelor's degree or higher in Bioinformatics, Computational Biology, Computer Science, or a related field.
• A Master’s degree or Ph.D. in a relevant discipline is preferred.
• Hands-on experience in bioinformatics workflow development, particularly with Nextflow, is required.
• Proven experience in programming using bash and Python in the context of NGS data analysis.
• Experience with version control system, particularly GitHub, for documentation and collaboration purposes.

TECHNICAL SKILLS REQUIREMENTS:
• Proficiency in developing bioinformatics workflow using Nextflow, with a strong understanding of its syntax, modules, processes, and configurations.
• Strong programming skills in Python.
• In-depth knowledge of bioinformatics tools commonly used in NGS data analysis, including BLAST, STAR, Bowtie, samtools, etc.
• Familiarity with high-performance computing environments (HPC) or cloud-based platforms.
• Proficiency in using version control systems such as Git for code management and collaboration.

Hard Skills:
1. Nextflow/Workflow scripting skills
2. Bioinformatics skill set
3. Python

Soft skills:
1. Communication (written/verbal)

Interview Process:
Teams Bridge with HM
Virtual/In-person (Panel)
IT Technical not Clinical / Scientific
20/hrs per wk (negotiable)

Company Description