Laboratory Manager- Waldor Lab

Matthew Waldor wants to understand the principles that govern the interactions between enteric bacterial pathogens and their hosts. Waldor and his team, based at Brigham and Women's Hospital develop animal models and integrate pathogen- and host-directed profiling methods to probe pathogen and host biology during infection. The team often applies and develops emerging technologies to define the genes, proteins, and metabolites that mediate interactions between pathogens and their hosts. Knowledge from these studies is applied in the development of new therapeutics, including a live-attenuated cholera vaccine now being studied in clinical trials. More information about the lab and their work can be found by visiting .

About the role:

As the Laboratory Manager you will supervise and perform technical and administrative tasks in the Waldor lab, providing support to Dr. Waldor and his laboratory staff, including postdoctoral fellows, research fellows, and graduate students. You will ensure adequate supplies for experimental needs and oversee equipment maintenance, and serve as liaison to HHMI and host institution administrative offices. Given the lab's work with enteric bacterial pathogens and animal models (primarily mice), you will help manage biosafety compliance and animal protocol documentation and may support laboratory research and procedures by performing routine experimental techniques, such as preparation of media, buffers, and stock solutions. You will assist Dr. Waldor with personnel management and will handle standard administrative paperwork, such as new student/fellow intake and reimbursement as well assist with writing animal protocols and overseeing the lab’s budget. The Lab Manager will also have the opportunity to have a primary role in research projects.

What we provide:

• A competitive compensation package with comprehensive health and welfare benefits.

• Joining the vibrant scientific communities of Brigham and Women's Hospital, Harvard Medical School, and the broader Boston biomedical research community.

• Opportunities for mentorship and professional development.

What you'll do:

• Manage day-to-day activities within the research laboratory, including ensuring the operation of essential equipment and making sure adequate supplies are available for routine experimental procedures.

• Maintain laboratory consumables and reagents inventories. Order and receive supplies and equipment.

• Act as liaison between the laboratory and host biosafety and regulatory offices (Environmental Health and Safety, IACUC, Institutional Biosafety Committee) to ensure compliance with all applicable regulations governing work with bacterial pathogens and animal models.

• Coordinate amendments and renewals for lab permits, licenses, and protocols, including animal protocols and biosafety approvals.

• Oversee service contracts and repairs of laboratory equipment. Maintain records of asset locations and participate in periodic asset inventories.

• Act as liaison between the lab and HHMI, and host institution administrative offices on issues such as procurement, MTAs, lab staff transitions, visas, budgets, and use of host accounts.

• Develop laboratory guidelines, maintain procedures manuals, evaluate new materials and equipment, and create process improvements for the lab.

• Train incoming personnel in proper lab conduct and, where applicable, in technical areas and complex processes; may plan for and provide working supervision to research technicians or other laboratory personnel of lower grade.

• Manage adherence to institutional biosafety and animal care and use standards, keep compliance records/logs current, maintain current knowledge of applicable health and safety regulations, and liaise with host regulatory offices to ensure compliance and participate in periodic regulatory review.

• Attend and participate in weekly lab meetings; the chosen candidate is also encouraged to engage in science projects.

What you bring:

• Bachelor's degree required, preferably in a health or physical science, a PhD in biomedical science is preferred.

• Three or more years of laboratory experience, including at least one year of supervisory experience, preferred.

• Interest in scientific work and the research being conducted by the lab.

• Strong organizational skills, attention to detail, and ability to plan effectively.

• Exceptional written and verbal communication skills, including the ability to initiate and compose written communications for various purposes in an appropriate style, along with strong record-keeping skills.

• Proficiency in Microsoft Office Suite (Word, Excel, Outlook).

• Ability to work inclusively and collaboratively with a diverse population and to succeed in a fast-paced, collaborative laboratory environment.

• Operational knowledge of advanced lab equipment.

• Ability to supervise others and develop instructional material for routine training purposes.

• In-depth understanding of organizational structure both within and outside the work unit, including the role of each position in the group and in other groups.

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.

#LI-LL1