Lab Manager

Overview

The Bandopadhayay and Beroukhim Labs ( and at DFCI (with co-affiliations with Boston Children’s Hospital and the Broad Institute) are seeking a joint Lab Manager to join our efforts to find better treatments for children and adults diagnosed with brain tumors. We apply cutting-edge genomic technologies to identify drivers of childhood and adult cancers, identify strategies to target these and to determine mechanisms of resistance to current and novel treatments. The aim of these efforts is to perform translational research to develop new therapies to improve outcomes of children diagnosed with these tumors. The work will be highly translational and span efforts from profiling the cancer genomes of pediatric brain tumors to determining new therapeutic targets, applying molecular oncology and functional genomic methodologies to determine oncogenic mechanisms and identify new dependencies, and to characterize mechanisms of resistance.

The ideal candidate will be passionate about developing a career of scientific discovery, a team player, enthusiastic about translational research to help improve patient outcomes, and highly self-motivated. They will coordinate the overall lab management for our teams. These tasks include (but are not limited to) overseeing lab ordering, managing of day-day tasks for lab operations, and onboarding/training for new staff. In addition, the ideal candidate will help drive forward scientific projects in collaboration with other scientists in our team, including single-cell/spatial technologies and high-throughput genetic perturbation approaches.

Responsibilities

• Manages team of RDSs to ensure correct sample inventories at large – blood and tissue derived.
• Manages all receiving, storage and retrieval requests, arranging sample transport, audits inventory of all samples, data entry in database systems, and placement of samples in correct temperature storage.
• Works with frequent users to maximize efficiency and batch requests when feasible.
• Responsible for receiving and tracking lab samples, managing freezer inventory, ordering necessary supplies, submitting billing charges, and assisting with ad hoc projects and reports.
• Hires and trains RDS staff for proficient sample management in all chains of custody.
• Responsible for managing, directing, and leading the RDS team.
• Collaborates with the Thub team for seamless specimen collections, inventories and transfers.
• Manages billing invoices to external and internal customers.
• Manages all equipment maintenance and schedules repairs as needed.
• Manages and updates biospecimen related SOPs.

Scientific Operations

• Assists PI in monitoring, enabling and facilitate collaborations with other programs.
• Active intellectual involvement in research projects is encouraged.

Administrative

• Responsible for managing efficient and effective administration of protocols and materials/stocks.
• Trains and manages RDSs and guides recruitment of technical staff.
• Responsible for annual reviews of technical staff performance.
• Assists PI with counseling, teaching, training, mentoring, orientation, in-service and continuing education for laboratory staff and trainees.
• Ensures all lab staff are compliant with mandatory trainings required by DFCI, NIH and sponsor(s).

SUPERVISORY RESPONSIBILITIES:

• Oversees 5-8 lab members

Qualifications

• Bachelor’s degree with at least 3 years postgraduate experience in molecular biology, cellular biology, cancer biology, or a related discipline.
• Enthusiastic, team player, innovative and analytical thinker, and self-motivated individual.
• Experience with cell culture and other models of human cancers, molecular oncology techniques and/or computational biology
• Excellent written and oral communication skills
• Excellent mentorship skills
• Candidate should have an outstanding academic and professional track record

Applicants are required to provide three referees at the time of application.

A minimum commitment of three years is strongly preferred.

KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:

• Exceptional people management and organization skills, with demonstrated ability to multi-task to enable many concurrent projects in a complex, fast paced environment.
• Excellent quantitative, analytic, and problem-solving skills to evaluate all aspects of a problem opportunity and make or facilitate appropriate and timely decisions.
• Excellent interpersonal skills, including the ability and willingness to work closely with other colleagues as a team; experience and comfort in working with individuals with diverse backgrounds and differing viewpoints; openness to new ideas.
• Proficiency in Word, Excel, PowerPoint.

Pay Transparency Statement

The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.

For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)

$88,000 - $110,100

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.