Research Associate/Senior Research Associate, In Vivo
- Execute in vivo studies using mouse models, including dosing, monitoring, and tissue collection at necropsy.
- Perform standard dosing and sampling techniques, including SC, IM, IV (retro-orbital), and IP injections, as well as submandibular bleeds and tail nick.
- Conduct or assist with small rodent surgical procedures (e.g., tissue transplantation/implantation); experience in this area is a key asset.
- Perform specialized tissue processing and imaging techniques, including immunohistochemistry (IHC) and immunofluorescence (IF) staining.
- Assess in vivo functionality, safety, and tumorigenicity of stem cell-derived cell product.
- Maintain and expand primary cell cultures using aseptic technique
- Perform cell isolation from primary human or mouse tissues for downstream analysis
- Conduct downstream biological assays to validate cell quality and function, including Flow Cytometry (FACS), RT-qPCR, and ddPCR, MSD/ELISA.
- Analyze biomarkers and signalling pathways to correlate in vitro characteristics with in vivo outcomes.
- Analyze complex datasets using statistical software (e.g., GraphPad Prism) and present findings to the scientific team.
- Maintain high standards of data integrity and ensure accurate documentation for research reports and study protocols.
- Contribute to the writing of study reports and participate in the strategic planning of long-term studies.
- Collaborate with cross-functional teams, support junior laboratory staff and interns, fostering a collaborative working environment.
- Human Connection : We respect and care for each other, our patients, and our communities. We believe teamwork empowers our joint success.
- Pioneering Spirit : We are trailblazers. We fearlessly push boundaries to overcome the limitations of existing therapies, fueled by passion and cutting-edge science.
- Always Learning : We believe collaboration drives innovation. Curiosity deepens our knowledge, and we benefit from our collective ideas and perspectives.
- Delivering on Our Promise : We are accountable to each other and the people we serve. We make a difference by delivering on our vision and elevating one another.
- Education: B.S. or M.S. in Cell Biology, Immunology, Regenerative Medicine, or a related discipline.
- Experience: 3–5+ years of relevant industry experience (Biotech/Pharma experience preferred).
- In Vivo Skills: Proficiency in rodent handling, multiple routes of administration (IV, IP, SC), and tissue dissection is required.
- In Vitro Skills: Hands-on experience with the isolation and culture of primary human cells or tissues is preferred.
- Analytical Skills: Strong experience with Flow Cytometry, qPCR, and microscopy. Ability to analyze data statistically and troubleshoot experimental variances independently.
- Other Skills: Excellent oral and written communication skills. Must be able to structure tasks, set priorities, and work effectively in a collaborative, team-oriented environment.
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