Principal Computational Biologist
Location: Boston, MA (Hybrid) This is an exciting opportunity to join a clinical-stage biotechnology company developing first-in-class therapies through a novel understanding of biology. Working at the forefront of drug discovery, the organisation combines cutting-edge biology with computational science to speed up the development of new treatments for patients. We are looking for a Principal Computational Biologist to lead the companies computational biology efforts. You’ll work alongside biologists and chemists using bioinformatics to drive drug discovery decisions and influence strategy. You will lead the design, execution and interpretation of complex bioinformatics analyses across multiple therapeutic programmes.
Key Responsibilities
- Partner with scientists to design computational strategies that answer key biological questions.
- Develop and implement bioinformatics pipelines for the analysis of multi-omics datasets.
- Evaluate and introduce emerging analytical methods and technologies where appropriate.
- Analyse RNAseq, proteomics, phospho-proteomics and whole genome sequencing data.
- Integrate pathway databases, network resources and published literature to generate meaningful biological insights.
- Present complex analyses in a clear and impactful way.
- Lead bioinformatics workstreams from conception through to delivery.
- Mentor junior team members.
- PhD in Bioinformatics, Computational Biology, Genomics or a related field.
- 4 or more years of post-PhD industry experience
- Strong programming skills in Python and/or R.
- Proficiency analysing bulk RNA-seq datasets.
- Expertise in statistical analysis of transcriptomics and proteomics data, including differential expression and pathway analysis.
- Experience integrating multi-omics datasets to answer biological questions.
- Strong understanding of molecular biology and drug discovery.
- Excellent communication skills with the ability to collaborate across multidisciplinary research teams.
This is a highly collaborative, hands-on role offering significant ownership and the opportunity to shape computational biology capabilities within a rapidly growing biotech, which you can grow with. Apply today to be considered.
Keywords: Bioinformatics / Bioinformatician / computational biology / computational biologist / RNAseq / RNA-seq / transcriptomics / single cell / singlecell / multiomics / multi-omics / proteomics / genomics / drug discovery / biotech / biotechnology / lead / principal / leadership
Recommended Jobs
Safety Coordinator
Job Description Job Description POSITION OVERVIEW The Safety Coordinator is the frontline champion of our "People First" culture. More than just a compliance officer, you are a proactive me…
Learning Facilitator, Questrom, Online MBA
The Online MBA (OMBA) program at Boston University's Questrom School of Business is an innovative program to bring an integrated graduate business curriculum to a global learning community at scale. …
Travel Registered Nurse CCU Job
Job Overview TLC Nursing Associates, Inc. is seeking an experienced Coronary Care Unit (CCU) Registered Nurse (RN) for travel assignments. This role is ideal for RNs specializing in critical card…
Catering Cook
Job Description Job Description Description: The Position: In the Commissary: As a Prep Cook, at Fireside Catering, you will be responsible for prepping ingredients for a wide variety of menu…
Recovery Support Worker
Job Description Job Description Overview Join a Team That Changes Lives For more than 170 years, Elwyn has been leading the way in supporting children, teens, and adults with autism, inte…
Community Health Instructor
Job Description Job Description Description POSITION SUMMARY: Under the direction and supervision of the Director of Community Health, the Community Health instructor will conduct safe, effec…
Event Staff
Join Ink Connect! Ink Connect is seeking an energetic and dependable Event Staff member to join our team in Boston, MA. This entry-level role is ideal for individuals who enjoy working with people, su…
Talent & Workforce Consulting Manager - Utilities
We Are: Talent Reinventors, and we help clients co-create the workforce of the future. How? We make decisions based on insights. We give people the tools and roadmaps to do their best work. We cre…
Partner Program Manager
Role Description & Responsibilities We are looking to add a new member to our Worldwide CRE team as part of our Go-to-Market organization. As our initiatives grow and responsibilities expand, the …
DESSERT COOK
Job Description Job Description Position Overview: The Dessert Cook is responsible for preparing and plating desserts according to recipes and restaurant standards. The ideal candidate has a…