Scientist - Neuroscience & Immunology

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

EMD Serono in Billerica, MA is seeking a Scientist to join the Discovery Biology group in Research Unit Neuroscience & Immunology (RU-N&I) team at our state-of-the-art research facility. The Scientist will contribute to the discovery of drugs for neurodegenerative/neuroinflammatory and autoimmune diseases. You will work collaboratively with an international team of scientists to develop novel therapeutics that align with the Neurology & Immunology portfolio. You will be responsible for the execution of in vitro cell-based assays that will further our mechanistic understanding of diseases and evaluate potential drug candidates.

Responsibilities:

• Plan, execute, and lead in vitro studies using human iPSC-derived cell types, or cell lines to support target validation and drug candidate evaluation efforts
• Conduct translational biomarker discovery using patient samples or disease-relevant cell-based assays to support pharmacodynamics and target engagement biomarker discovery
• Operate a variety of laboratory equipment, including microscopes/automated imagers, flow cytometers, qPCR machines, and spectrophotometers
• Record data accurately in the Electronic Laboratory Notebook and maintain records per company policy and legal requirements
• Prepare data reports and presentations to lab heads, project teams, and at external meetings
• Independently design, execute, analyze, interpret, and troubleshoot experiments to support pipeline progression
• Provide technical support to colleagues in own area of expertise when necessary
• Work closely with members in RU-N&I to support departmental goals

Who You Are:

Minimum Qualifications:

• Master's degree in Biology, Neurobiology, Immunology or other Science discipline with 2+ years of laboratory experience in Academia, Pharma, Biotech or CRO

OR

• PhD in Biology, Neurobiology, Immunology, or other Science discipline with 1+ years of laboratory experience in Academia, Pharma, Biotech or CRO

Preferred Qualifications:

• Demonstrated experience with human iPSC-derived neural disease models
• Knowledge and hands-on experience in the following areas:

• • Maintaining mammalian cell culture:

• • • • Primary neurons or glia
      • Co-culture and triculture systems
      • PBMCs

• • Transfection of cells to introduce siRNAs, ASO, or CRISPR-based gene editing tools to suppress or knockout specific genes
  • Live-cell imaging and imaging analysis experience using an Incucyte or similar automated imager
  • Immunocytochemistry and/or RNAscope
  • Gene expression and protein analyses: DNA/RNA isolation, qPCR platforms (Applied biosystems QuantStudio, Nanostring, etc.), western blotting (SallySue, Wes)
  • Bioanalytical assays: AlphaLISA, Meso Scale Discovery (MSD)

• Pharmaceutical industry/ Drug discovery experience
• Experience on a pipeline project team
• Proficient with research analytical software: GraphPad Prism, Microsoft Office, FIJI (or other image analysis software), QuantStudio
• Demonstrated ability to work independently in a self-motivated, pro-active manner
• Comfortable with designing and executing experiments based on protocols provided by literature, seminars, and/or other scientists
• Good understanding of basic drug discovery principles
• Enthusiasm, curiosity, and passion for exploring new biology with relevance to human disease
• Desire, demonstration of ownership, accountability, and ability to work efficiently in a fast-paced, high functioning cross-functional team
• Excellent interpersonal and written communication skills

Pay Range for this position: $83,500 - $134,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!