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Research Associate, Therapeutics Translational Research

BioSpace
Cambridge, MA
The Role

Moderna is seeking a motivated Research Associate (RA) with a strong background in immunology and spectral flow cytometry to join the Therapeutics Translation Research (TxTR), Experimental Immunology group. This role requires hands-on expertise in complex immune profiling and functional assays using primary human immune cells. The successful candidate will play a critical role in assay development, execution, and data generation to support key program and project decisions.

Here's What You’ll Do

  • Design and execute high-parameter spectral flow cytometry assays to characterize human immune cell phenotypes and functions.
  • Develop and implement robust sample processing workflows and data analysis pipelines to minimize technical variation.
  • Perform and analyze experiments independently; troubleshoot and document results in an electronic lab notebook.
  • Troubleshoot experiments and diligently record results in electronic lab notebook.
  • Act as a technical lead for cytometry assay development, QC and instrument maintenance.
  • Analyze high-dimensional flow cytometry data using tools such as OMIQ.
  • Establish and perform orthogonal immune cell functional assays to support flow cytometry data, such as MSD, EliSpot/FluoroSpot and co-culture assays.
  • Conduct high-parameter spectral cell sorting for downstream applications, including single-cell sequencing.
  • Help draft and optimize SOPs for immune assays.
  • Collaborate across cross-functional teams and contribute to regulatory submissions, reports, and presentations.
  • Promote a safe, compliant, and organized lab environment.
  • Faithfully document scientific work and contribute to reports, presentations, and regulatory submissions

Here’s What You’ll Need (Minimum Qualifications)

  • BA/BS in Immunology, Biology, Life Sciences, or related field.
  • Hands-on experience with primary human immune cells and functional assays; industry experience is highly preferred.
  • Proven expertise in spectral and conventional flow cytometry and cell sorting, ideally with human samples.
  • Familiarity with mRNA therapeutics is a plus.

Here’s What You’ll Bring To The Table

  • Experience in immunoassays and primary human immune cell processing, especially T cells.
  • Proficiency in high-parameter flow cytometry assay development and readouts (e.g., ICS, cytokine bead arrays, ELISAs).
  • Hands-on use of Cytek Aurora and Cytek CS instruments.
  • Strong skills in flow cytometry data analysis, particularly using OMIQ.
  • Prior experience with cell sorting for downstream single-cell applications is highly preferred.
  • Excellent collaboration, communication, and organizational skills.
  • A growth mindset and passion for contributing to a transformational, high-impact biotech environment.
  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Lifestyle Spending Accounts to personalize your well-being journey
  • Family planning and adoption benefits
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities
  • Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model 

 As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

Posted 2025-09-02

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