Senior principal data scientist real

Johnson & Johnson
Cambridge, MA

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function

Data Analytics & Computational Sciences

Job Sub Function

Data Science

Job Category

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America

Job Description

Johnson & Johnson Innovative Medicine R&D Data Science and Digital Health is recruiting for a Senior Principal Data Scientist, Real World Evidence (RWE) .

The primary location for this position is flexible – Titusville, NJ; Raritan, NJ; Spring House, PA; Cambridge, MA; or San Diego, CA. May consider remote on a case by case basis

J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, immunology, neuroscience, cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners and from clinics to hospitals. To learn more about Johnson & Johnson Innovative Medicine visit

The R&D Data Science & Digital Health, Real-World Evidence (RWE) team at J&J Innovative Medicine is dedicated to developing innovative evidence solutions and critical insights through diverse data sources, including RWD, trial data and emerging innovative data sources, to support clinical programs and regulatory decision-making. The Senior Principal Data Scientist will collaborate closely with strategic partners in R&D Data Science and Digital Health, as well as multidisciplinary teams within J&J Innovative Medicine, to develop and implement evidence and insights to improve patient outcomes and accelerate clinical development in Oncology, Immunology, or Neuroscience.

Key Responsibilities

  • Be a hands-on technical leader, leading a portfolio of RWE projects while developing best practices and common technical tools
  • Support the development of the R&D RWE strategy for the generation and utilization of RWE for our key pipeline assets
  • End-to-end expertise in RWE studies (external control arm, novel endpoints, trial design optimization) including conceptualizing research questions, data feasibility, study design, analysis, programming, and interpretation
  • Assess treatment patterns and unmet needs using RWE to inform asset positioning
  • Ensure RWE generation aligned with regulatory requirements and scientific standards
  • Identify evidence opportunities and develop innovative evidence programs to support early development, registration, and post-marketing phases
  • Shape the selection of real-world data sources, establish data quality standards, and ensure data robustness and relevance for clinical research
  • Lead and develop junior researchers and programmers in executing strategies to develop RWE from concept through publication
  • Support regulatory interactions and meetings with scientific data packages and expertise


Required Qualifications

  • A Ph.D. degree, or master’s degree in a quantitative field (e.g., epidemiology, biostatistics, statistics, or similar)
  • Relevant experience (4+ years for Ph.D., 6+ years for a master’s) within biopharma companies, RWE consulting firms, or other relevant healthcare industries
  • Extensive hands-on experience with data engineering and exploratory data analysis, statistical modeling, time-to-event analyses, comparative effectiveness analyses, causal inference methods
  • Demonstrated expertise with multiple real-world data sources
  • Expert proficiency in R and SQL
  • Familiarity with data structure and programming of clinical trial data
  • Strong communication and influencing skills, capable of inspiring teams and driving cross-functional alignment
  • Highly motivated and intellectually curious, with strong executional rigor and a passion for solving complex challenges


Preferred Qualifications

  • Familiarity with drug discovery and the clinical development process
  • Expertise in oncology, Immunology or Neuroscience drug development
  • Experience in regulatory-grade evidence, communicating and responding to agency reviews and comments


Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.  

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([email protected]) or contact AskGS to be directed to your accommodation resource.

#JRDDS

#JNJDataScience

#JRD

Required Skills

Preferred Skills:

Advanced Analytics, Consulting, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Mentorship, Strategic Thinking, Tactical Planning, Technical Credibility

The anticipated base pay range for this position is :

$137,000 - $235,750

Additional Description For Pay Transparency

Additional Description for Pay Transparency Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

  • Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
  • Employees are eligible for the following time off benefits: – Vacation – up to 120 hours per calendar year – Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year – Holiday pay, including Floating Holidays – up to 13 days per calendar year – Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below.


Posted 2025-11-09

Recommended Jobs

Senior Accountant (Manufacturing/Gov't Contracting experience required)

Ondek Solutions
Natick, MA

Are you a meticulous financial professional ready to make an impact at the core of a forward-thinking tech and engineering company? We are on the lookout for a dynamic Senior Accounting Specialist…

View Details
Posted 2025-09-12

Medical Assistant

NITELINES USA, INC
Devens, MA

NEEDED: Medical Assistant LOCATION: 42 Patton Road, Devens, Massachusetts 01434 SCHEDULE: Monday – Friday, five (5) days per week, eight (8) one (1) hour sessions per day, normally between the …

View Details
Posted 2025-09-05

Front Desk Agent

JP & RB Motel Investments, LLP
Sturbridge, MA

Job Description Job Description Immediate Opening for a friendly, enthusiastic person to work 3PM to 11PM shifts at Front Desk/ Receptionist at a small family owned hotel in the heart of Sturbrid…

View Details
Posted 2025-07-24

Operations Manager

Snow & Sons Landscaping
Greenfield, MA

Are you ready to grow your career with a company that values their team, produces quality work, and prioritizes customer satisfaction? Snow & Sons Landscaping is seeking a motivated and personable O…

View Details
Posted 2025-09-25

Community Health Educator, Cardiology (per diem)

Boston Medical Center
Boston, MA

Position: Community Health Educator, Cardiology Location: Boston, MA Schedule: Per Diem, On-site About Bmc At Boston Medical Center (BMC), our diverse staff works together for one goa…

View Details
Posted 2025-11-09

Wealth Management Client Associate (FP)

Bank of America Corporation
Beverly, MA

Merrill Wealth Management is a leading provider of comprehensive wealth management and investment products and services for individuals, companies, and institutions. Merrill Wealth Management i…

View Details
Posted 2025-10-24

Utility Network GIS Consultant, Manager Save for Later Remove job

PwC
Boston, MA

At PwC, our people in business application consulting specialise in consulting services for a variety of business applications, helping clients optimise operational efficiency. These individuals an…

View Details
Posted 2025-10-14

Certified Caregivers (HHA or CNA)

Senior Helpers-Boston North & Southeastern MA
Newburyport, MA

HIRING Certified Caregivers (HHA or CNA) for clients in multiple Seacoast / North Shore towns including: Essex, Ipswich, Newburyport, Marblehead, Swampscott, etc. As a Caregiver with Senior Helpers…

View Details
Posted 2025-09-12

Process Assistant

Amazon.com Services LLC
Everett, MA

DESCRIPTION Our Worldwide Operations network delivers millions of packages and smiles to Amazon customers every day. We are looking for motivated, customer-focused individuals who want to join our…

View Details
Posted 2025-09-26

Bench Chemist

Actalent
Hadley, MA

Job Description Job Description Job Title: Bench Chemist Location: Hadley, MA Job Type: Contract-to-Hire Schedule: Monday–Friday, 8:00 AM – 5:00 PM Overview: We’re seeking a detai…

View Details
Posted 2025-11-04