HR Generalist

Twist BioScience
Quincy, MA
Twist is seeking a dedicated and experienced HR Generalist to provide comprehensive Human Resources support for our Global workforce. This role is critical in ensuring the smooth daily operation of HR functions, compliance with labor regulations, and a positive employee experience across the assigned areas. This position will report to the SVP of HR.
Key Responsibilities
Employee Relations & Performance Management
  • Primary Point of Contact: Serve as the first point of contact for routine employee and manager inquiries regarding HR policies, procedures, benefits, and general employment matters.
  • Employee Relations Triage: Triage and manage basic employee relations issues, including initial investigations, documentation, and coordination with HR leadership to ensure timely and fair resolution.
  • Performance Support: Assist managers with routine performance management processes, including coaching on documentation, delivery of feedback, and implementation of Performance Improvement Plans (PIPs).
HR Operations & Administration
  • Onboarding/Offboarding: Assist in the full employee lifecycle administrative processes, including new hire onboarding (paperwork, system entry, orientation) and offboarding (exit interviews, final documentation, system termination).
  • Policy Implementation: Assist in communicating, interpreting, and ensuring consistent application of company policies and procedures across the assigned areas.
  • Benefits & Leave Administration: Act as an administrator for employee benefits inquiries and coordinate leave administration (e.g., medical leave, short-term disability) in compliance with relevant regulations.
Compliance & Reporting
  • Mandatory Training: Coordinate and track completion of mandatory compliance training for assigned employees.
  • HR Reporting: Assist the HR team in generating routine and ad-hoc HR reports related to headcount, turnover, compensation, and other key HR metrics.
Qualifications & Experience
  • 3+ years of progressive experience in a Human Resources role, with at least 2 years as an HR Generalist supporting a professional workforce.
  • Business Acumen: Experience supporting corporate/administrative functions is preferred.
  • Foundational knowledge of relevant employment laws and labor regulations.
  • Proficient in using HRIS systems (e.g., ADP, Workday, etc.), Applicant Tracking Systems (ATS), and Microsoft Office/G Suite.
  • Strong interpersonal, organizational, and communication skills (written and verbal). Must have a high level of integrity and the ability to handle confidential information with discretion.
  • Bachelor's degree in Human Resources, Business Administration, or a related field.
  • Certification (Preferred): Professional HR certification (e.g., PHR, SHRM-CP) is a plus.
The base cash compensation for this Massachusetts-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

Massachusetts Pay Range

$78,000—$92,500 USD
Posted 2025-12-11

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