Synthetic Organic Chemist (Boston)

Quadratic 3D, Inc.
Boston, MA

Description

We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins . This position involves rapid exploration of chemical space through organic synthesis to develop photochemical and photophysical structure-property relationships. This role will be particularly appealing to chemists with a passion for both synthetic and physical organic chemistry. Our process uses a small amount of each lead candidate, so synthetic creativity is not limited by the scalability concerns that usually narrow the available chemical space in materials applications.

Responsibilities

  • Design, execute, and troubleshoot small molecule synthetic routes, with a focus on divergent or modular approaches to rapidly generate lead candidates.
  • Characterize lead candidates via UPLC, NMR, UV/Vis and IR spectroscopy, and mass spectrometry.
  • Contribute to the development of high-throughput analytical capabilities, small molecule databases, and virtual libraries.
  • Work with cross-functional teammates to explore photochemical and photophysical structure–property relationships that drive 3D printing performance.
  • Mentor junior scientists.
  • Maintain excellent electronic lab notebook documentation.

Minimum Qualifications

  • PhD in Organic Chemistry or BS in Chemistry and 5+ years of experience in a small molecule discovery role.
  • Strong expertise in both synthetic and physical organic chemistry, demonstrated through publications and other activities.
  • Significant experience designing and executing multi-step synthetic routes.
  • Extensive experience with modern computing and data analysis tools relevant to synthetic chemistry.
  • Excellent communication, organizational, and time management skills.
  • Demonstrated ability to independently drive an idea from conception to project completion.
  • Evidence of strong collaboration and teamwork talents/skills.
  • Strong publication record, both as lead author and as contributor to other projects .

Preferred Qualifications

  • Expertise in photochemistry and/or radical chemistry.
  • Significant experience with synthesis of heterocyclic and/or extended aromatic systems, especially those relevant to organic (opto)electronics.
  • Experience with cheminformatics and/or computational chemistry tools (e.g. DFT) relevant to the production of structure-property relationships.

Benefits

  • We offer competitive compensation packages in our VC-backed startup.
  • Benefits include a full suite of offerings covering medical, dental, vision and 401k plan.
  • Beautiful setting looking out over a river and seaport; outdoor seating and picnic areas.
  • Highly collaborative work environment.

Additional Information

  • Travel: Occasional travel may be required from time to time
  • Location: Boston, Massachusetts

We value diversity in our company and are an Equal Opportunity Employer.

Posted 2026-04-27

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