Scientist I, Immunosafety

AbbVie
Worcester, MA
Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Evaluate immunosafety risk potential of candidate therapeutic large molecules employing in vitro immunosafety assays to support development of preclinical molecules.

  • Execute human cytokine release assays including whole blood- and PBMC- based formats.
  • Conduct complement activation assays, troubleshooting and optimizing as needed.
  • Perform cell subset isolation protocols on human whole blood or PBMC samples.
  • Conduct T cell proliferation assay usings isolated cells.
  • Analyze experimental data and maintain accurate documentation, placing data in proper scientific context through review of relevant literature and reporting findings at team meetings.

Qualifications

  • B.S. in Biological Sciences, Cellular Immunology, or related field with typically 5 years of experience, or Master’s Degree or equivalent education with typically two years of experience.
  • Understanding of cellular immunology with an emphasis on blood cell subsets and T cell biology.
  • Experience with whole blood-based cell assays, blood cell isolation, and serum cytokine readouts.
  • Experience with multicolor flow cytometry panel design, BD LSRFortessa instrument operation, BD FACSDive and FlowJo software, and flow cytometry data analysis.
  • Excellent interpersonal and oral/written communication skills.
  • Results-oriented work ethic and a positive "can-do" attitude with a strong sense of urgency and self-motivated desire to achieve common business goals.
  • Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time ofthis posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of anybonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's soleand absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

Posted 2026-01-23

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