Associate director

Your Experience Includes…

• PhD in a biological or related discipline e.g., Biology, Biochemistry, Chemistry, Biotechnology or Pharmaceutical Science with 5+ years’ industry experience after postdoc.
• Experience in LC-MS based bioanalysis of proteins, oligos or small molecules is required.
• Excellent knowledge and hands-on experience in sample preparation techniques such as immuno-enrichment, beads extraction and LC/MS based method development and qualification/validation for proteins, oligos or small molecules.
• Proven ability to troubleshoot complex scientific challenges and manage multiple priorities.
• Deep understanding of the FDA/EMA regulatory requirements for bioanalytical and biomarker assays and current industry practices.
• Excellent organizational, communication and leadership skills.
• Proficiency of using Sciex Triple Quadrupole LC-MS/MS system and Thermo Orbitrap mass spectrometers such as Q Exactive series or Exploris series.
• Experience working in LNP-based gene therapy therapeutics is a plus.
• Experience with lab automation technologies is a plus.
• Experience in people management is a plus.
• Experience with downstream statistical and bioinformatics analysis is a plus.
  
  

You are interested in…

• Develop, optimize, and validate bioanalytical methods to measure proteins, oligos, and lipids in biological samples, including cells, biofluids, and tissues, to support the development of preclinical and clinical programs.
• Lead a team of four PhD scientists conducting LC-MS analyses. Drive internal non-GLP bioanalytical activities to support PK, PK/PD and Biodistribution studies, ensuring timely project completion.
• Guide CROs to develop and validate LC-MS-based assays that support GLP toxicology studies, clinical bioanalytical measurements, and clinical biomarker readouts.
• Review and approve study plans, assay validation reports, and bioanalytical study reports. Author bioanalytical sections of regulatory submissions.
• Manage documentation of internal assay protocols, ROPs, qualification plans, and sample analysis reports.
• Collaborate with Formulation, Oligos Chemistry, Delivery, Pharmacology, Regulatory, Analytical Development and Platform teams to initiate and advance LC-MS assay work.
• Manage an LC-MS lab of four mass spectrometers, two Hamilton Stars and one Kingfisher Apex.
  
  

About you:

We are seeking an Associate Director of Bioanalytical with strong LC-MS expertise to join our DMPK/Bioanalytical group at Tessera Therapeutics. This role will lead a LC-MS team of 4 PhD scientist to design, develop and qualify new LC-MS bioanalytical assays for gene editing therapeutics and related novel modalities (proteins, oligos and lipids) to support both non-regulated and regulated pharmacokinetic (PK), toxicokinetic (TK), and biomarker measurement. The ideal candidate will possess strong technical proficiency, independent problem-solving skills, and a collaborative mindset, and must be comfortable working in a fast-paced environment that demands attention to detail, adaptability of priorities and the ability to manage priority shifts.

Tessera leaders are empathetic and transparent coaches with a strong sense of integrity. They are committed to the growth and development of their teams, the organization and themselves.

Leadership Structure:

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.

Gang Sun, PhD - Executive Director, DMPK/Bioanalytical

Dr. Gang Sun has over 16 years of experience in DMPK and Bioanalytical, working with diverse drug modalities including small molecules, proteins, oligosaccharides, and lipid nanoparticles across various therapeutic areas such as oncology, immunology, and gene editing. He has supported discovery, preclinical, and clinical programs. He currently leads a multidisciplinary team at Tessera Therapeutics, overseeing DMPK, bioanalytical, proteomics, biomarker, and clinical pharmacology support for Gene Writing and Rewriting Therapeutics development. Previously Dr. Sun held roles at Translate Bio, Corbus Pharmaceuticals, Merrimack Pharmaceuticals, Merck & Co., and Covance. He holds a Ph.D. in Chemistry from Peking University, an M.S. from Qingdao University of Science and Technology, and a B.S. from Qingdao University.

Meet our Leadership Team and Board of Directors

Meet your Talent Partner:

Ben Hoogheem – Senior Director, Head of Talent Management

As Head of Talent Management at Tessera Therapeutics, Ben leads Tessera’s talent strategy across talent acquisition, performance management, and talent mobility.

Ben began his career as an in vivo Pharmacologist, which gave him a lasting appreciation for the rigor, creativity, and collaboration that drive scientific discovery. That foundation continues to shape how he helps build organizations designed to enable science thrive.

Ben is focused on aligning exceptional people with bold science – creating the structure, clarity, and culture that empower teams to scale effectively and achieve meaningful impact.

Compensation:

The stated base salary range represents Tessera’s good-faith estimate for this role. Actual compensation will be determined based on a number of factors, including but not limited to individual qualifications, years of relevant experience, internal compensation alignment, and external market data.

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness, and financial security of our employees and their families. Benefits currently include group medical, vision, and dental coverage; group life and disability insurance; a 401(k) plan with company contribution; tuition reimbursement; and more.

This position is also eligible for an annual incentive bonus and equity grants as part of Tessera’s total rewards program.

Per Year Salary Range: $164,000 - $199,000 USD

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or [email protected]

Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.