Senior Scientist II, Biologics In Vitro Technologies

BioSpace
Worcester, MA
Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The Biologics Discovery Sciences Group at AbbVie is seeking an accomplished scientist to contribute significantly to the conception, execution, and communication of antibody discovery strategies in a highly collaborative environment. The successful candidate will develop and execute research strategies to advance the discovery and development of therapeutic antibodies for AbbVies core therapeutic areas. Key responsibilities include designing and executing in vitro display technologies for lead antibody identification and optimization. The candidate is also expected to generate internal and external collaborations to further program goals and drive antibody discovery programs within a multidisciplinary research group in a dynamic, fast-paced team setting.

Key Responsibilities

  • Implement novel selection strategies and build industry-leading libraries for discovery and screening of therapeutic candidates.
  • Identify and solve technical problems independently; conceive and implement innovative research ideas.
  • Leverage expertise to develop and execute research for a detailed mechanistic understanding of therapeutic molecules' molecular pharmacology.
  • Provide project updates, analyses, and advice to cross-functional teams and senior management.
  • Present original work across departments and at scientific conferences; may author or co-author peer-reviewed scientific papers or patents.
  • Manage scientist(s), evaluate team performance, and ensure effective performance of the team.
  • Ensure consistency and quality of technical reports.
  • Engage with internal and external scientific leaders in collaborative research.
  • Serve as a biologics lead for cross-functional teams and contribute scientific insights into projects across various therapeutic areas; recognized as an expert in the discovery and engineering of therapeutic molecules.

Qualifications

  • PhD, MS, or BS degree in Biochemistry, Biochemical Engineering, or related disciplines with typically 4-6(PhD), 10-12+ (MS), or 12-14+ (BS) years of experience.
  • Hands-on experience with in vitro antibody discovery display technologies (e.g., phage, yeast, mammalian).
  • Extensive experience and knowledge in antibody engineering and optimization, including humanization and Fc optimization.
  • Expertise in antibody and/or antibody fragment library design and construction.
  • Strong molecular biology skills.
  • Experience in displaying complex proteins (non-antibody-like) is preferred.
  • Familiarity with sequence analysis tools such as Geneious and PipeBio.
  • Experience with flow cytometry.
  • Ability to explore and develop new approaches to advance innovative in vitro discovery and screening technologies.
  • Excellent organizational skills and ability to manage multiple projects simultaneously.
  • Team player with the capability to operate in a fast-paced, multi-disciplinary environment and across functional and therapeutic areas.
  • Adaptability to rapid changes in project priorities and timelines.
  • Recognition in the scientific community, evidenced by a record of peer-reviewed publications and patents, is preferred.
  • Highly developed leadership and managerial experience is preferred.
  • Strong ability to engage with internal and external scientific leaders in collaborative research.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

  • The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
  • This job is eligible to participate in our short-term incentiveprograms.
  • This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

Posted 2025-09-24

Recommended Jobs

Senior Project Manager

Spectra Infosystems
Boston, MA

Job Description Job Description Company Description Our company is a leading IT services, consulting and outsourcing company delivering exceptional business solutions and customer value to i…

View Details
Posted 2025-07-26

“Join the Healthcare Wave in Vibrant Jamaica Plain!”

NurseRecruiter
Jamaica Plain, MA

Sterile Processor Allied job in Jamaica Plain, MA Join the healthcare wave in vibrant Jamaica Plain as a Sterile Processing Technician! Embrace the fulfilling travel nursing lifestyle, where you’ll m…

View Details
Posted 2025-08-20

Physician Assistant, General Surgery - Per Diem

Cambridge Health Alliance
Everett, MA

Requisition Number: CHAP-2296 Cambridge Health Alliance is an award-winning public healthcare system in Boston’s metro north communities, providing innovative primary, specialty and emergency care …

View Details
Posted 2025-08-07

Senior Research Technician

Dana-Farber Cancer Institute
Brookline, MA

Overview The Targeted Protein Degradation (TPD) Proteomics Core within the Fischer Lab at Dana-Farber Cancer Institute serves as a resource for the Cancer Biology Department, aiding investigat…

View Details
Posted 2025-09-21

Lia Toyota Northampton - Automotive Service Manager

The Lia Group
Northampton, MA

Lia Toyota Northampton is seeking experienced Service Manager to join our team. If you're looking for a fast-paced, professional, and positive environment that rewards hard working, reliable, and t…

View Details
Posted 2025-09-24

HVAC Lead Installer

Carl F Riedell And Son Inc
Osterville, MA

Job Description Job Description Riedell is looking to hire an HVAC Lead Installer Lead a crew and advance your career at Carl F. Riedell & Son in Osterville, MA. Can you install Mitsubishi Min…

View Details
Posted 2025-07-25

Tellers to Assistant Branch Managers - 3 locations

Adams Community Bank
Great Barrington, MA

J ob Description: Looking for a stimulating new job that will challenge and fulfill you? Look no further, you found us! We are an employee and customer focused savings bank and are experiencing a…

View Details
Posted 2025-08-28

Direct Support Professional - Halifax, Pembroke, Weymouth, MA

All Care Homecare, LLC
Halifax, MA

Job Description Job Description Direct Care Aide - Halifax, Pembroke, Weymouth, MA Part-time positions / Weekends / Mom Hours Entry-level Direct Care Aide (DCA) earn $17/hour Some experi…

View Details
Posted 2025-09-15

Production Material Handler 1: 1st Shift

Milliken and Company
Salisbury, MA

Milliken & Company is a global manufacturing leader whose focus on materials science delivers tomorrow’s breakthroughs today. From industry-leading molecules to sustainable innovations, Milliken crea…

View Details
Posted 2025-09-12

Remote Prin Supply Chain Proj Analyst

Planet Group
Danvers, MA

HM's Top Needs: #Blue Yonder  /  JDA Technical  /  Deployment experience with ESP (not WMS Not TMS) # Functional experience  (as a planner/ buyer / scheduler) # Worked on large projects Ed…

View Details
Posted 2025-08-27