Director, Corporate Controller

Manifold Bio is a dynamic biotech company building a pipeline of targeted biologics using a novel in vivo-centric discovery approach. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.

Position

We are seeking a strategic and hands-on finance leader responsible for building and scaling the company's accounting infrastructure, financial reporting, and internal controls. This role also includes foundational FP&A responsibilities, supporting budgeting, forecasting, and financial planning activities in close partnership with the CFO and department heads. This position offers the unique opportunity to build robust financial systems from the ground up while working at the intersection of cutting-edge protein engineering. The ideal candidate will thrive in our collaborative, science-driven culture while bringing the financial rigor and strategic thinking necessary to support our ambitious growth plans.

Responsibilities

Accounting & Controls:

• Lead all aspects of accounting operations, including general ledger, payroll, accounts payable/receivable, and fixed assets


• Develop and implement scalable accounting policies, procedures, and systems appropriate for a pre-IPO biotech company


• Own the monthly, quarterly, and annual close processes, ensuring accuracy and timeliness


• Prepare GAAP-compliant financial statements and manage external audits


• Establish and maintain internal controls and ensure compliance with regulatory requirements

FP&A & Strategic Finance:

• Support the annual budgeting and quarterly forecasting processes across departments


• Partner with R&D, G&A, and other functional leaders to develop and monitor operating budgets


• Prepare financial models and scenario analyses to support strategic decision-making


• Assist in cash flow planning and long-range financial planning


• Contribute to board and investor reporting packages with financial insights and variance analysis

Cross-Functional Leadership:

• Collaborate with Legal, HR, and Lab Operations to ensure financial integrity across the organization


• Support fundraising activities, investor reporting, and IPO readiness


• Manage and mentor a growing accounting and finance team

Required Qualifications

• Bachelor's degree in Accounting or Finance, engineering; CPA required


• 10+ years of progressive accounting experience, including leadership roles in biotech or life sciences


• Strong knowledge of US GAAP and technical accounting


• Experience in a pre-IPO or high-growth startup environment preferred


• Familiarity with FP&A processes and financial modeling


• Excellent communication and leadership skills


• Experience with ERP systems (e.g., Quickbooks, NetSuite)

If you're excited to support breakthrough protein technologies through strategic financial planning, help build partnerships that advance our drug development goals, and contribute to our mission of advancing breakthrough treatments, please apply!

We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.