Principal- Biorepository Operations, Precision Medicine

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Principal, Biorepository Operations – Precision Medicine

• Position is fully remote but if local to Waltham, MA there could be opportunities for in person meetings.

Job Summary

The Principal, Biorepository Operations – Precision Medicine provides enterprise-level leadership and strategic oversight for biorepository operations supporting precision medicine programs and research registries. This role owns the end-to-end operational framework governing the biospecimen lifecycle—from clinical site collection through logistics, biorepository oversight, laboratory processing coordination, data generation interfaces, and long-term inventory management.

This role reports to the Head of Precision Medicine and works closely with the Chief Medical Officer (CMO) and other members of the senior leadership team to ensure operational alignment with scientific priorities, clinical objectives, regulatory requirements, and customer commitments. The Principal operates with significant autonomy and influence, shaping strategy, capabilities, and execution across matrixed organizations.

Key Responsibilities

Enterprise Strategy & Operational Leadership

• Define and drive enterprise strategy for biorepository operations supporting precision medicine initiatives.
• Establish operating frameworks, governance models, and best practices to ensure scalability, quality, and compliance.
• Anticipate future scientific, clinical, and customer needs and translate them into operational capabilities.

End-to-End Biospecimen Lifecycle Ownership

• Provide strategic oversight of the full biospecimen lifecycle including, clinical site collection, laboratory analysis, data generation and quality control, customer delivery and long-term storage.
• Ensure seamless integration across multiple internal and contract partners including Clinical Operations, Analytic Laboratories, Informatics, Data Management, Quality, and additional partners.
• Set expectations for performance, quality, and reliability across all biospecimen operations.

Leadership, Influence & Organizational Enablement

• Serve as a trusted advisor to the Head of Precision Medicine, CMO, and senior leadership.
• Influence leaders and teams across matrixed organizations without reliance on direct authority.
• Represent biorepository operations in governance forums and strategic planning discussions.

Quality, Compliance & Risk Governance

• Ensure compliance with GCP, IRB, ISO, and precision medicine governance frameworks.
• Partner with Quality and Compliance teams to maintain audit readiness and manage risk.
• Champion data integrity, traceability, and documentation rigor.

Technology & Digital Enablement

• Set strategic direction for LIMS/BIMS, inventory systems, and analytics platforms.
• Collaborate with IT and Informatics teams to improve system integration and data visibility.
• Promote adoption of innovative technologies to improve efficiency and scalability.

Customer Engagement & Business Development Support

• Serve as an operational SME in customer meetings and governance discussions.
• Support proposal development, feasibility assessments, and solution design.
• Contribute to the evolution of precision medicine and biorepository service offerings.

People & Capability Leadership

• Enable and develop leaders and teams across biorepository operations.
• Promote a culture aligned with Thermo Fisher values of Integrity, Intensity, Innovation, and Involvement.
• Support succession planning and long-term organizational capability.

Qualifications

• Master’s degree required (MS, MPH, MSc, in a scientific field)
• 10+ years of experience in biorepository operations, biospecimen management, clinical research, or precision medicine.
• Demonstrated enterprise-level leadership and influence in matrixed environments.

Preferred Qualifications

• PhD or equivalent degree in a scientific field.
• Experience supporting precision medicine programs, registries, observational research, or large-scale biospecimen initiatives.
• Experience contributing to business development and customer-facing solution design.

Role Scope & Impact

• Enterprise-level ownership of biorepository operations supporting precision medicine.
• Significant influence on scientific outcomes, customer experience, and operational scalability.
• Trusted partner to the Head of Precision Medicine, CMO, and Senior Leadership

Thermo Fisher values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary for typical working hours.
• Ability to use and learn standard office equipment and technology with proficiency.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
• May require travel. (Recruiter will provide more details.)

Compensation and Benefits

The salary range estimated for this position based in Massachusetts is $160,000.00–$180,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: