Scientist, Protein Sciences

Bristol-Myers Squibb Company
Cambridge, MA

Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

The successful candidate will play a key role within the downstream purification function of the Discovery Protein Science group, supporting a wide range of therapeutic programs. Responsibilities will span early drug candidate and exploratory molecule generation using traditional and automated purification systems, to lead candidate process development. Extensive experience in protein purification and process development is required for this role as well as the ability to operate, troubleshoot and develop novel automation systems and solutions. A background in AKTA/Unicorn programming and liquid handler operation will be helpful but the candidate must have a strong interest in automation and a proven track record of innovation and problem solving.
  • Perform manufacturability assessments as part of enabling package for therapeutic candidates transitioning to the Biologics Development organization.
  • Utilize and continuously develop automated systems and strategies for high throughput multi-step purification, sample handling, and protein analytics.
  • Protein production for mid-stage Discovery programs to support cyno tox studies, concentratability, PK/PD, formulation/analytical development etc.
  • Perform mid-scale purification for the evaluation and comparison of early Discovery therapeutic candidates.
  • Deliver on reagent requests to support Discovery programs.
  • Troubleshoot downstream purification processes and chromatography instrumentation.
  • Support upstream mammalian expression efforts when necessary.
  • Contribute to the continuous improvement effort for the Discovery manufacturability assessment in collaboration with Manufacturing Development.
  • Participate in the preparation of technical reports, summaries, protocols, and regulatory documents, where necessary.
  • MAJOR SKILLS REQUIRED:
  • B.S. in a scientific discipline and at least 5 years of relevant laboratory experience or M.S. with at least 3 years of relevant experience preferred.
  • Protein purification experience including method development, optimization, and the ability to troubleshoot standard purification protocols and instrumentation.
  • Experience with larger scale protein production (CMC, and tech transfer experience is a plus).
  • Hands on experience in the operation and control of chromatography workstations (AKTA, BioRad, etc.).
  • Experience utilizing laboratory automation for protein purification, high throughput process development and protein analytics is a plus.
  • Excellent technical, organizational, and analytical skills are required.
  • Protein characterization experience (biophysical, spectroscopy, protein assays, SDS-PAGE)
  • Experience with LIMS and Electronic Notebook is a plus.
  • Excellent communication skills, evidence of innovative thinking, and ability to work with a sense of urgency under tight deadlines.

The starting compensation for this job is a range from $128,420 - $155,600, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Careers Site.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as "Transforming patients' lives through scienceā„¢ ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [click to reveal email address] [email protected] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Posted 2025-07-28

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