Research Associate II (Scientific)

job summary:
We are seeking a motivated Bioinformatics Research Associate II to join the Next Generation Sequencing (NGS) Core group to support genomic analyses of multiple therapeutic modalities within the Genomic Medicine Unit (GMU) CMC organization. The role is responsible for leading the analysis of gene therapy driven projects, interfaced within a cross-functional team, to develop and implement genomic analytical solutions for programs spanning precandidate selection through late phase clinical development. The ideal candidate will be expected to support end-to-end NGS analysis solutions, through analytical pipeline design and execution. Strong independent problem solving and troubleshooting skillsets are preferred.

location: Waltham, Massachusetts
job type: Contract
salary: $53.00 - 55.53 per hour
work hours: 9 to 5
education: Bachelors

responsibilities:

• Support computational needs for the development and validation of NGS-based assays.
• Work closely with a multi-disciplinary team of scientists and engineers to implement genomic analytical solutions for programs spanning precandidate selection through late phase clinical development.
• Develop, execute, and maintain NGS analysis pipelines for execution in cloud-based computational environments.
• Keep records of development work and testing in a GxP environment utilizing electronic notebook solutions.
• Represent the group at internal meetings.

qualifications:

Required:

• Degree in a relevant computer science discipline with a minimum of 3 years of relevant industry experience
• Minimum of 1 year experience with NGS, spanning knowledge and hands-on dry-lab experience
• Expertise in bioinformatics with a working understanding of genomic analysis solutions (e.g., FastQC, Bowtie2, SAMtools, NCBI BLAST+, Nextflow, etc.)
• Scripting experience in coding languages (e.g., bash, awk, Python, R, etc.)
• Understanding of NGS platforms, specifically those utilizing the synthesis by sequencing technique (i.e., Illumina platforms)

Preferred Qualifications:

• Familiarity with the software development lifecycle (e.g., Git)
• Automated unit testing for test driven design (TDD)
• Familiarity with basic molecular biology techniques (e.g., ligation, PCR, and qPCR) as well as nucleic acid extraction and analysis techniques (e.g., Nanodrop, DNA fragment analyzers, ddPCR, etc.)
• Knowledge of and experience with other sequencing platforms (i.e., SMRT sequencing)
• Prior experience in leading the internalization of custom NGS analysis pipelines is highly preferred
• Wet-lab method development experience to support NGS workflows

skills: Polymerase Chain Reaction (PCR), Chemistry Manufacturing and Controls (CMC)


Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact [email protected].


Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).


This posting is open for thirty (30) days.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.