Biologist
Location : Boston, MA
Work schedule: Mon - Fri 9am - 5pm
Pay Range : $50.00 - $55.80/hr
Type: Contract, Potential for extension or conversion to permanent Requirements
- Bachelor’s degree in Immunology, Cell Biology, or a related field plus 5 years of relevant experience in biotechnology, pharmaceutical industry, or academic research in the field of immunology.
- Master’s degree in Immunology, Cell Biology, or a related field plus 2 years of relevant experience in biotechnology, pharmaceutical industry, or academic research in the field of immunology.
- Prior experience with using live cell analysis platforms such as Incucyte and Xcelligence will be a plus
- Proficient in developing in vitro assays, including work with human cell lines, PBMCs, and whole blood assays.
- Proven ability to utilize immune cell and cytokine analytical techniques, including multiplex ELISA, MSD and flow cytometry
- Prior work with CRISPR/Cas9 gene editing techniques.
- Prior work with cell culture; Primary and mammalian cell lines
- Strong analytical, problem-solving, and decision-making skills.
- Excellent interpersonal and communication skills.
- Ability to work independently and collaboratively within a team environment
As a Sr. Scientist in Immunology, you will support the development of novel allogeneic cell therapies by developing immune cell-based assays, executing in vitro experiments, and assessing immune response to different gene edited cells. You will contribute to the early-stage validation of gene edits and will work closely with cross-functional teams to advance cell therapy programs to preclinical development.
- Develop and optimize cell-based assays using primary human immune cells, such as mixed lymphocyte reaction, T-cell, NK-cell cytotoxicity assays, phagocytosis assays, etc.
- Isolate and culture different immune cells from either PBMCs or fresh whole blood using immunomagnetic isolation techniques.
- Perform differentiation of monocyte to macrophages or dendritic cells, as needed
- Assess immune checkpoint receptor expression using multi-parameter flow cytometry techniques
- Use different gene editing techniques, including CRISPR to create knockouts or transgenic cell lines
- Gene edit different cell types including iPSCs, primary cells, and immortalized cell lines
- Use different methods, including cell sorting, single cell cloning to create gene edited clonal cell lines
- Design and execute experiments and analyze resulting data to evaluate efficacy of gene edited cells in in vitro assays
- Communicate experimental data effectively through written reports and oral presentations.
- Demonstrate flexibility and motivation to learn and apply new technologies for biological assays.
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan. Ref: #558-Scientific
Recommended Jobs
Event Bartenders
Consider It Done Staffing is currently seeking energetic and highly motivated individuals to join our mixology team. The ideal candidate will have a passion for great service, a strong work ethic, an…
Experienced Garage Door Installer
Job Description Job Description Leading Garage Door Company that offers excellent pay and benefits is seeking EXPERIENCED garage door installer. Compensation ranges between $18 to $23 per hour…
2026 Internship
About Us Baker Newman Noyes (BNN) is a top 100 tax, assurance, and advisory firm in the U.S. and holds a Best of Accounting™ recognition for superior client service. BNN was founded to create opportu…
Associate Director/Lead, US Solid Tumor Forecasting, Global Oncology
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Tak…
Retail Mortgage Loan Officer
Are you currently a productive loan officer wanting to take your business to the next level? If so, join the team at Mutual of Omaha Mortgage. We are part of the iconic brand and nationally recogni…
RN Field Clinical Care Coordinator - Boston, MA and surrounding areas
Job Description At UnitedHealthcare, we’re simplifying the health care experience, creating healthier communities and removing barriers to quality care. The work you do here impacts the lives of mill…
Explore Tranquil Watertown as a Therapy Assistant!
Certified Occupational Therapy Assistant job in Watertown, MA As a Certified Occupational Therapist Assistant in picturesque Watertown, you’ll embark on an exciting journey each day. Imagine starting…
Fulltime Patient Care Specialist up to $27/hr
Fulltime Patient Care Specialist up to $27/hr Highlights: Role: Patient Care Specialist Compensation: up to $27/hr Stockbridge, MA Responsibilities: Support indi…
Security - Roslindale, MA
Rainbow USA is recognized as one of the fastest growing junior, kids, plus, and petite, specialty apparel retail chains and has grown to over 1,000 retail stores! We have multiple retail lines that pr…
Software Engineer III
About this role: Pickle is on the hunt for a dynamic and driven Software Engineer III to revolutionize the future of warehouse automation. You’ll design and develop algorithms that enable our robots…