Lab Operations Manager
Parabilis Medicines
Cambridge, MA
Why Join Us? Parabilis Medicines, Inc is a biopharmaceutical company pioneering the discovery and development of Helicon peptide therapeutics; these ultra diverse alpha-helical peptides are capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions. Through Helicon therapeutics, Parabilis is poised to revolutionize the medical possibilities for patients by precisely drugging intracellular targets long understood to be significant drivers of disease but never before drugged due to the limitations of existing drug modalities to act within the cell. FOG-001, the company's first-in-class TCF-blocking β-catenin inhibitor, is being evaluated in a Phase 1/2 study for patients with advanced solid tumors, including desmoid tumors and colorectal cancer. Parabilis is fully leveraging the unprecedented potential Helicons present by deploying proprietary, custom-built machine learning and computational methods as part of its discovery and development process. Parabilis Medicines has raised more than $500 million to date from leading life sciences investors. Parabilis is headquartered in Cambridge, Mass. What's the opportunity? The Lab Operations Manager will focus on strategic procurement, inventory systems, vendor partnerships, safety protocols, and regulatory compliance. Reporting to the AD, Research Operations, this individual will serve as a critical operational leader and bridge between scientific teams, operations, finance, and suppliers—ensuring the lab environment is resourced, compliant, and optimized for cutting-edge research and programs. The ideal candidate brings a blend of scientific understanding and operational expertise, with a strong track record in driving continuous improvement, developing standard operating procedures (SOPs), and leveraging data for strategic decisions. Procurement & Vendor Management
- Manage end-to-end procurement of reagents, consumables, chemicals, equipment, and specialty supplies.
- Evaluate and onboard new vendors, ensuring scientific compatibility and compliance with internal policies. Negotiate vendor contracts to optimize cost, lead time, and service quality. Collaborate with Finance and Procurement teams to maintain budget alignment and approval workflows.
- Monitor and report on vendor KPIs (e.g., delivery timeliness, quality issues, pricing trends), and drive corrective actions where needed.
- Coordinate customs, import/export logistics, and cold-chain shipments for regulated or overseas materials.
- Develop and manage a robust inventory control system for reagents, consumables, cell lines, plasmids, kits, and other lab materials. Forecast usage, set reorder points, plan buffer stock, and minimize product expiration or overstock.
- Lead the development, implementation, and maintenance of SOPs for inventory handling, stock control, access, and disposal protocols.
- Conduct scheduled inventory audits and resolve variances through root cause analysis.
- Oversee cold storage operations (–80°C, –20°C, liquid nitrogen, cold rooms), including tracking, access, and safety protocols.
- Supervise vendor and process for compliant disposal of expired or hazardous materials.
- Coordinate and plan onboarding safety programs for new hires, ensuring timely integration into lab safety, EH&S, and compliance frameworks. Monitor and reinforce adherence to environmental, health, and safety (EH&S) regulations across lab operations. Sit on the company's cross-functional safety committee.
- Maintain records and documentation to support inspections, audits, and internal reviews.
- Drive continuous improvement initiatives across procurement, inventory, and workflows.
- Provide metrics reports and dashboards covering spend analysis, usage trends, procurement performance, and operational KPIs. Identify and implement opportunities for cost savings, vendor consolidation, or process automation.
- Bachelor's degree in Life Sciences, Chemistry, Engineering, or related field.
- 9+ years of experience in lab operations, inventory and vendor management, and procurement in biotech, pharma, or academic research settings.
- Excellent data analysis and reporting, organizational and communication skills with cross-functional teams.
- Foundational knowledge of EH&S lab standards, hazardous materials handling, and cold-chain logistics.
- Solid understanding of international shipping regulations, IATA standards, and customs coordination.
- Preferred: Advanced degree. Experience in drug discovery environments. Familiarity with lab informatics systems and their integration.
- Able to work on-site and attend in-person meetings.
- Growth-Minded . We're inventing a new class of medicines—one applicable to therapeutic targets that have been dreamt about, but always considered impossible to drug. Our work requires us to be curious, humble and adaptable.
- In(ter)dependent. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
- Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.
- All-In. We're All-In on solving some of the hardest scientific challenges and delivering one of the most effective new classes of drugs in history.
Posted 2025-10-22
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