Molecular

Moderna, Inc.
Cambridge, MA

The Role

Support biomarker and bioanalytical next‑generation sequencing (NGS) for mRNA therapeutics. You will contribute across wet‑lab execution and computational analysis—helping to prepare samples and libraries, operate sequencing workflows, assay development, maintain LIMS‑driven traceability, and assist with bioinformatics and AI‑enabled QC/reporting.

Here’s What You’ll Do

  • Perform nucleic‑acid extraction, quantification from variety of biological matrices, QC (e.g., TapeStation/Bioanalyzer), and prepare libraries for RNA‑seq, WES/targeted DNA, TCR‑seq, and HLA typing.
  • Operate Illumina platforms (e.g., NextSeq/NovaSeq); track run metrics; troubleshoot and support instrument maintenance/calibration.
  • Support bioinformatics pipelines (FASTQ→alignment/calling/quant); assist with RNA‑seq differential expression, TCR clonotype analysis, HLA typing, and SNP/variant calling.
  • Maintain data integrity and chain‑of‑custody in LIMS; ensure metadata hygiene and audit‑ready records.
  • Explore AI/ML for read‑level QC, anomaly detection, and automated reporting (stretch opportunity).
  • Draft/update SOPs; summarize results for cross‑functional partners; present progress at team meetings.
  • Follow GDP, biosafety, and data governance practices appropriate to bioanalytical/clinical environments.

Here’s What You’ll Need (Basic Qualifications)

  • Enrolled in Undergraduate or Graduate program in Molecular Biology, Genomics, Bioengineering, Computational Biology, or related field.
  • Coursework or hands‑on experience with at least one NGS modality (RNA‑seq, WES/targeted DNA, SNP genotyping, HLA typing, or TCR‑seq).
  • Comfort with standard molecular techniques (pipetting, bead cleanups, qPCR) and QC instrumentation.
  • Strong organization, communication, and meticulous record‑keeping.
  • At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.

Here’s What You’ll Bring to the Table (Preferred Qualifications)

  • Experience with one or more of: RNA‑seq, WES/targeted panels, TCR‑seq, HLA typing, SNP genotyping; familiarity with tools such as STAR/Salmon, BWA/GATK, MiXCR, OptiType (or equivalents).
  • LIMS experience (e.g., Benchling, LabVantage) and clean data provenance practices.
  • Bioinformatics basics with FASTQ/BAM/VCF handling, QC (FastQC/MultiQC), and environment management (conda/mamba).
  • Exposure to AI/ML for omics (scikit‑learn/PyTorch/TensorFlow) or LLM‑assisted lab/analysis workflows.
  • Clear scientific communication with figures/tables suitable for non‑expert audiences.
  • At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship. 

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Free premium access to meditation and mindfulness classes
  • Subsidized commuter benefits
  • Generous paid time off, including:
  • Vacation, sick time and holidays
  • Volunteer time to participate within your community
  • Discretionary year-end shutdown
  • Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. 

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.
Posted 2025-10-06

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