Accounting Manager

Fractyl Health
Burlington, MA

Position Summary

We are looking for an Accounting Manager who will help oversee day-to-day accounting operations and ad-hoc accounting activities. Working closely with the Assistant Controller, the Accounting Manager will play a key role in the monthly financial close, external and internal reporting, and contribute to on-going process improvements and projects.

Key Responsibilities


  • Key player in the monthly, quarterly, and annual close processes, including preparation of journal entries, accruals (especially for R&D and clinical trials), and account reconciliations

  • Assist with overseeing the accounts payable function, ensuring timely and accurate processing of invoices, adherence to company policies, and appropriate coding of expenses

  • Prepare and maintain supporting schedules for key accounts, including prepaids, fixed assets, and accrued liabilities

  • Support timely preparation of financial statements in accordance with US GAAP

  • Play a key role in implementing new processes and systems

  • Aid in improvement of documentation of processes to support internal controls

  • Coordinate with external auditors during interim and year-end audits

  • Mentor junior staff and potentially oversee one or more accountants over time

  • Perform other related duties and ad-hoc projects as required

Qualifications


  • Bachelor’s degree in Accounting or Finance; CPA or CPA-track preferred

  • 4–6 years total experience, ideally including public accounting and/or biotech/pharma industry exposure

  • Prior experience managing or supporting the accounts payable process, preferably in a growth-stage or biotech environment

  • Familiarity with biotech-specific topics such as R&D accruals, clinical trial accounting, or SOX readiness is a plus

  • Strong understanding of US GAAP

  • Experience with ERP systems (Microsoft Dynamics 365 preferred)

  • Eagerness to grow professionally and take on increasing responsibility

Knowledge and Skills


  • Highly organized and detail-oriented with a passion to deliver quality results.

  • Strong proficiency with Microsoft Excel

  • Ability to work with confidential information in a professional way

  • Effective team player – puts personal agenda aside and focuses on what’s best for the team


  • Desire and ability to work in a fast-paced environment. Ability to prioritize tasks effectively, managing multiple assignments simultaneously, and consistently delivering high-quality results within established timeframes.

Compensation


This position offers a competitive salary in the range of $125,000 – $135,000 annually, along with a comprehensive benefits package. Actual compensation will be based on relevant experience, education, and market factors.

The description and requirements outlined above are general; additional requirements may apply.

In accordance with Massachusetts law, General Laws Chapter 149, Section 19B. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Posted 2026-02-07

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