Research Associate II
Global Discovery Pathology is seeking a qualified individual to assist with the execution and analysis of microscopy-based cell, organoid, and tissue assays aimed at understanding therapeutic targeting and mechanism of action. The candidate will work with a cross functional team of imaging scientists, histologists, and pathologists to support a wide range of different therapeutic areas within the *** research organization. The candidate must possess an M.S. degree in cell and molecular biology or a related field and have 2+ years of laboratory experience. Experience with cell culture, general molecular biology techniques, immunostaining, and basic fluorescence microscopy is required. Experience with complex in vitro models (organoids or lab-on-a-chip systems), advanced microscopy techniques such as confocal and super resolution, and comprehensive image analysis including AI-based approaches will be highly beneficial. Daily responsibilities will include preparation of common stock solutions, maintenance and preparation of cell cultures, immunofluorescence staining of samples (cultured cells, tissue sections, and 3D samples comprising thick tissue samples or whole organoids), data acquisition using both automated and human-interactive microscopy systems, and organization and analysis of image data. Additional responsibilities involving operation of an automated liquid handling system for sample preparation may also be incorporated depending on the candidate's knowledge, experience, and ability. After initial training to familiarize them with lab-specific processes, the candidate will be expected to conduct their work independently following consultation with more senior lab members with whom they will be working. The successful candidate will have excellent time management skills, record keeping and communication skills, and a willingness to learn new techniques. They will have the opportunity to present their work both within the department and at cross functional project meetings. The primary work schedule will consist of standard business hours, onsite five days per week. Occasional experimental schedules may require additional off-hour work. Interested individuals should submit a resume along with contact information detailing their qualifications.
Must-Haves • Candidate should have 2+ years of laboratory experience (not fresh out of school) • Maintenance and preparation of cell cultures • Immunofluorescence staining of samples Nice to Have Skills: • Experience with fluorescence microscopy • Strong proficiency in confocal microscopy • Advanced skills in live-cell imaging • Ability to work with complex in vitro models • Experience performing image analysis
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