Scientist II, Radiochemistry (preclinical)
- Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)
- Paid time off policy including holidays and sick time
- Internal growth and development programs & trainings
- 401(k) program, life & accident insurance and disability insurance
Key responsibilities include working safely and compliantly with radioactive materials and operating essential lab equipment such as HPLC and Radio-TLC. Key Responsibilities:
- Execute and manage the production of radiotracers used in PET/SPECT imaging and therapeutic research studies.
- Develop and validate:
- Contribute to the design, development, and optimization of radio labeled compounds targeting complex biological markers for application in PET/SPECT imaging and therapeutic studies.
- Synthesis of novel PET/SPECT and therapeutic radiopharmaceuticals
- Purification methods for small and large molecules
- Analytical methods for HPLC and TLC
- Release criteria for imaging studies
- Dose formulation processes
- Operate and maintain analytical and automated radiochemistry synthesis units.
- Stay current on advancements in radiochemistry and imaging through literature review and attendance at scientific conferences.
- Maintain clear, accurate, and up-to-date records.
- Analyze data, recognize aberrant results, and propose corrective actions or next steps
- Summarize data for reports, papers, and presentations.
- Manage multiple projects simultaneously and prioritize tasks effectively
- Mentor and guide junior team members.
- Provide scientific expertise and troubleshooting internally and in communication with Sponsors related to radiochemistry.
- Perform other duties as assigned.
- Experience with small and large molecule radiochemistry labeling, purification, and formulation
- Working knowledge and experience with HPLC and TLC techniques in radiochemistry
- Experience in conjugation with chelators and labeling with radiometals is preferred.
- Prior experience with F-18 radiochemistry and radioiodination methods is considered advantageous.
- An effective team player with the ability to collaborate across various departments
- Ability to multi-task different projects and manage time effectively
- Strong written and verbal communication skills that can reach an audience of varying levels of expertise
- Ph.D. in Chemistry or relevant field with 3+ years or M.S. with 5+ years of experience in an academic or pharmaceutical lab
- Experience working with radioactive materials in a safe and compliant manner
- Ability to lift more than 40 pounds
- Proficient with Microsoft office
- English: Fluent
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