Manager, Single Cell Research & Operations

The Manager, Single Cell & Research Operations will
be responsible for implementing changes into both clinical and research
processes, providing scientific leadership for new experimental design,
interpreting data, and ensuring the development of robust operational processes
that align with scientific and organizational goals.

Characteristic Duties:

· Process
Implementation & Workflow Management

· Responsible
for implementing changes to New Protocols & Products and Workflow Changes.

· Plan
validation experiments, assess changes statistically, and work with Automation,
LIMS, and SQM to implement process changes.

· Document
work performed and maintain quality standards, including training lab teams in
a timely manner.

· Troubleshooting
across the entire area of focus.

· Assist
with supply chain alternatives, create reagent phase-in QCs, and be responsible
for ordering new reagents.

· Maintains
up-to-date Bills of Materials related to any process changes or updates and
monitors usage.

Scientific Design & Research Contribution

· Designs
new experiments with more complex and moderately advanced scientific knowledge.

· Interprets
data, presents results of research, and draws conclusions regarding presented
material and nature of work.

· Understands
how to build processes that are robust while mindful of how they may impact
future processes and fit into scientific and organizational goals.

· Makes
significant contributions to scientific papers, reports, posters, and
presentations.

· Participates
in the writing of grant proposals and patent applications.

· Participates
in external activities such as scientific conferences, technical meetings,
invited symposia, etc.

Communication & Collaboration

· Works in
collaboration with the Director, Process Development to approve changes and
ensure they meet long-term goals.

· Collaborate
with various teams (Quality & Compliance, Automation, LIMS, SQM, GS, Lab
team, ODI) to assess timelines, workflows, and communicate project updates,
needs, and issues.

· Works
closely with the Supervisor/General Supervisor daily to communicate project
updates, resource needs, issues, etc.

Education, Mentoring & Supervision

· May train,
supervise, or mentor junior members of the team.

· Work with
GS to identify competent PDAs to work with on experiments and delegate tasks
to.

· Listen to
feedback from the lab and assess feasibility of requested changes.

Qualification Requirements:

· PhD
required

· At least 5
years of related experience working in a research lab focusing on lab
histology, genomics, molecular biology, flow cytometry and imaging.

· At least 3
years of management related experience overseeing the work of others in a lab
setting.

· Experience
with all commercial single cell RNA assays including but not limited to 10X
Genomics, BD Rhapsody, and Fluent

· Experience
with library construction and sequencing is required

Strong understanding of histology best practices and instrumentation

· Demonstrated
ability to design and optimize flow cytometry panels, including high parameter
spectral panels

· Knowledge
of spatial techniques and current instrumentation

Pay Range: 104,000 - 145,333 Usd Annual

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact [email protected] for assistance.