Back to Jobs

Senior/Executive Director, Program Management (EU/US)

Prilenia
Boston, MA
About Prilenia

Prilenia, a private biopharmaceutical company with a highly committed and talented global team, is seeking a Senior/Executive Director, Program Management located in Europe, Israel or the United States, east coast location is strongly preferred.

Being part of Prilenia is being a part of a simple but urgent mission – the development of transformative medicines for people affected by devastating neurodegenerative diseases. Driven by an unwavering commitment to scientific excellence, Prilenia is developing pridopidine, a first-in-class potentially neuroprotective sigma-1 receptor (S1R) agonist, which, if approved by the EMA later this year, could be the first approved drug to impact clinical disease progression and not just manage symptoms.

Prilenia holds Orphan Drug designation for pridopidine in HD and ALS in the U.S. and EU. In addition, pridopidine has received Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of HD. The European Medicines Agency (EMA) has accepted for review Prilenia’s European Marketing Authorisation Application (MAA) seeking regulatory approval of pridopidine for the treatment of HD. This is the first submission seeking approval for a potential treatment that can impact clinical progression in HD. For ALS, Prilenia also plans to initiate a pivotal Phase 3 trial to evaluate pridopidine.

To learn more about our story and company culture, visit us at We seek an experienced Program Management lead to join our team as Senior/ Executive Director Program Management . This role will lead integrated program management for Prilenia across the various development programs and indications, providing end-to-end oversight of program strategy and management. It is a strategic and operational role that would serve as partner to the leadership team in driving the project plans, priorities and coordinated execution. This role will initially report to the Company’s COO.

The ideal candidate will have significant prior experience in driving program management, including working with growing, late-stage biotech companies; a collaborative, “can do” mindset and ability to drive decision making in fast-paced environment.

  • The position's level will be determined according to the candidate's experience.

Roles And Responsibilities

  • Develop and implement the overall program management strategy aligned with company objectives.
  • Build and maintain integrated programplans for all programs. Work closely with the leadership team and program teams to define, track and maintain integrated program workstreams.
  • Oversee the planning, execution, and tracking of multiple cross-functional programs through clinical development and commercialization.
  • Drive timelines and monitor resources to keep programs on schedule and budget. Proactively identify and resolve challenges within the program teams. This includes developing and maintaining integrated documentation, such as Gantt charts, decision logs, and risk registries
  • Conduct continuous review and analysis of critical path activities. Communicate any perceived risks to budget or timeline to management in a timely manner.
  • Provide operational expertise to the program team, continuously improving project standards, processes, metrics, and practices in order to deliver projects and programs according to plan and within budget.
  • Build and maintain tools to monitor and communicate program progress to the program team and all levels of the organization, including developing presentations for leadership.
  • Serve as PMO of program teams and of the Development Management Team, working with program leads and leadership team to facilitate cross-functional program meetings (including distribute agendas, maintain meeting minutes, and drive follow up toward completion of action items).
  • Ensure effective, proactive and open communications, to achieve transparency and clarity of program goals, progress and issues. Establish key metrics and monitor performance, through dashboards and reports to enable timely information and analyses for senior leaders.
  • Facilitate discussion and productive conflict around program strategy, deliverables, and timelines to enable commitment and alignment.

Qualifications

  • 15+ years of in-depth pharmaceutical industry experience and drug development in a program management role.
  • BA/BS degree with an advanced degree preferred. MSc or advanced scientific degree a plus. PMP certification is a plus
  • Prior experience leading and managing global, cross-functional late-stage clinical development programs (preferred: including leading to regulatory approvals)
  • Experience in small/growing biotech companies is a must.

Skills

  • Proven ability to communicate clearly and present key information objectively to all levels of the organization including executive management.
  • Demonstrated ability to positively influence outcomes, key project decisions, and strategic problem-solving.
  • Proactive risk management with ability to propose solutions and deliver appropriate mitigation plan.
  • Ability to communicate (written and verbal) with impact to provide appropriate context, articulate views, drive clarity, and address barriers to progress program development.
  • Ability to drive decision-making within a cross-functional and cross-cultural, global team structure.
  • Excellent organizational skills and attention to detail, while keeping the strategic view

Location/Time Zones:

This is a full-time,remote position in either the US, Europe or Israel. This role will require occasional in-person/face-to-face meetings. Flexible schedule with interactions across North America, Europe and Israel time zones. Occasional travel throughout North America and Europe is required.

Prilenia operates across the United States, Canada, Europe and Israel, is incorporated in the Netherlands and backed by leading life sciences investors. We are a highly virtual and flexible organization that is mostly remote and encourages team members to work in the ways that make them most effective, with a focus on our common goals and getting the job done.

Prilenia is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. We are dedicated to fostering a diverse, inclusive, and welcoming workplace for all.
Posted 2025-09-28

Recommended Jobs

Entry Level Account Rep

GREAT HILL CONSULTING GROUP
Burlington, MA

Job Description Job Description Great Hill Consulting Group is looking for a results-driven sales representative to actively seek out and engage client prospects. We're seeking an enthusiastic, c…

View Details
Posted 2025-09-22

Bilingual Sales Associate (Spanish)

Sherwin-Williams
Hingham, MA

Bilingual Sales Associate (Spanish) Location Hingham, MA : Store associates work closely with wholesale and retail customers to determine their needs, answer their questions about Sherwin-Williams pro…

View Details
Posted 2025-09-27

Accountant

D2b Groups
Westport, MA

D2B Groups is on the lookout for a detail-oriented Accountant to enhance their client's dynamic finance team. The successful candidate will be responsible for a variety of accounting tasks, including…

View Details
Posted 2025-09-12

Accounts Receivable Coordinator

Williston
Easthampton, MA

The Williston Northampton School, an independent co-educational boarding and day school located in Easthampton, MA, has a full-time, calendar-year opening for an Accounts Receivable Coordinator. Th…

View Details
Posted 2025-09-12

Locum Tenens Hospitalist Job Northampton, MA

CompHealth CompHealth
Northampton, MA

When it comes to finding the perfect locums assignment, sometimes it is all about who you know. CompHealth has been around for a long time and have a vast network of connections to facilities across t…

View Details
Posted 2025-09-23

Carpenter Experienced

TradeSource, Inc
Amesbury, MA

We are seeking a highly motivated, detail-oriented individual for the role of skilled carpenter. This carpentry position will include frame to finish in a commercial or residential setting. We off…

View Details
Posted 2025-09-24

Full-Time Retail Associate 010524

The UPS Store Franklin #0738
Franklin, MA

Retail Sales Associate / Supervisor FT / PT with flexible availability (Some Saturday & Sundays required) If you have worked at The UPS Store before, definitely call us for this opportunity! T…

View Details
Posted 2025-08-28

Licensed Practical Nurse (LPN) - $45/hr

ProPivotal Staffing
Chelsea, MA

Licensed Practical Nurse (LPN) - $45/hr Ready for a change? Our brand-new, state-of-the-art facility is looking for dedicated LPNs to join our team. Conveniently located with a bus stop right out …

View Details
Posted 2025-09-21

Locum Tenens Family Practice Job MA

Weatherby Healthcare Weatherby Healthcare
Massachusetts

Weatherby Healthcare is currently seeking a Family Practice Physician in MA If this opportunity sounds right for you, give us a call today to speak with an expert Weatherby consultant for details. …

View Details
Posted 2025-09-10