Senior Program Manager

Landmark Bio
Watertown, MA

Job Description

Job Description

We are seeking a self-driven, team-oriented, and entrepreneurial-minded Senior Program Manager to join Landmark Bio. The Senior Program Manager has an in-depth understanding of the processes and systems required to manage complex programs and projects, including extensive experience with Smartsheet, along with a functional understanding of the technical aspects of cell and gene therapy programs and awareness of Landmark Bio’s business objectives.

The Senior Program Manager will support cross-functional program execution by driving operational coordination, maintaining program management tools and documentation, and serving as a key liaison between internal teams and external clients. This role is responsible for managing timelines, dashboards, communications, and process improvements while ensuring programs are executed efficiently and effectively.

Responsibilities
  • Support the planning, coordination, and execution of internal and client-facing programs
  • Develop and maintain program timelines, schedules, dashboards, and risk registers with support from senior program managers
  • Coordinate program materials and shared resources, escalating constraints and risks as appropriate
  • Generate and maintain documentation for program scope changes and client communications
  • Assist with capturing and sharing lessons learned across programs to improve operational efficiency
  • Create and update presentations for team meetings, leadership reviews, and client discussions
  • Serve as a Smartsheet super user for the organization, creating, managing, and optimizing complex workflows, automations, dashboards, and reporting tools
  • Develop and maintain program management resources including trackers, templates, dashboards, presentation materials, and other operational tools
  • Evaluate and recommend process improvements to enhance team collaboration, visibility, and efficiency
  • Collaborate cross-functionally on new system evaluations, tool implementations, and training initiatives
  • Maintain internal Microsoft Teams sites and external SharePoint client sites to ensure documentation is organized, current, and accessible
  • Archive program documentation at the close of programs in accordance with internal procedures
  • Own and maintain program management documentation including:
    • Program charters
    • Program plans and schedules
    • RACI matrices
    • Risk registers
    • Business requirements
    • Policies and procedures
    • Training materials
  • Ensure all documentation is accurate, complete, version-controlled, and properly stored
  • Serve as the primary point of contact for assigned clients
  • Coordinate and manage client meetings, teleconferences, and onsite visits
  • Prepare agendas, meeting minutes, action items, and follow-up communications
  • Build collaborative relationships with internal stakeholders and external partners to support successful program delivery
  • Assist in training personnel on evolving program management tools and systems
  • Develop training materials including slide decks, guides, and reference documentation
Qualifications
  • BS degree with 7+ years relevant experience (GMP pharmaceutical, biologics, and/or cell and gene therapy field) is required
  • PMP certification desired
  • High degree of proficiency in Smartsheet is required, including advanced skills in workflow design and implementation, template creation and management, user training and support, and reporting and analytics
  • Strong communication, problem solving, planning, and project management skills
  • Ability to support more than one project of a reasonable size simultaneously

Landmark Bio is dedicated to translating cutting-edge research into life-changing therapies. The company provides CMC development and GMP manufacturing capabilities for cell and gene therapies and other novel modalities, and partners with academic, biotech, and industry collaborators to advance next-generation manufacturing technologies.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Posted 2026-06-19

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