Manager, Payroll

Madrigal Pharmaceuticals
Waltham, MA

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) a serious liver disease that can progress to cirrhosis liver failure need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigals medication Rezdiffra (resmetirom) is a once-daily oral liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic inclusive and high-performing culture that values scientific excellence operational rigor and collaboration. To support our continued growth we are strengthening our workforce strategy to ensure we have the right talent at the right time in the right way.

Job Description Title: Payroll Manager

Department: Payroll

Job Overview: The Payroll Manager is responsible for supporting data management related to aspects of employee payroll processing within an organization. This position reports directly to Payroll Director.


Position Responsibilities:

  • Process U.S. multi-state on-cycle payroll (semi-monthly) for 850 employees including Puerto Rico using ADP WFN.
  • Prepare Out-of-cycle payroll (RSU NQ ISO Termination).
  • Ensure all payroll data is accurate including employee hours deductions and benefits.
  • Investigate and resolve payroll discrepancies in a timely manner.
  • Implement system improvements to streamline payroll processes and enhance efficiency.
  • Assist in 401K Audit and Workers Compensation Audit.
  • Prepare Journal entries and accruals related to payroll and equity.
  • Conduct month end account reconciliations.
  • Assist Payroll Director with quarter-end Year-end activities including W-2 reconciliation.
  • Provide excellent customer service by addressing payroll-related inquiries and resolving issues in a timely manner.
  • Partner with HR for equity reporting or discrepancies.
  • Staying up-to-date with federal state and local regulations governing payroll benefits equity and ensuring compliance with all relevant laws.
  • Generating regular reports on payroll and benefits metrics for management review as well as preparing reports for external stakeholders such as auditors or regulatory agencies.
  • Providing support to employees regarding payroll and benefits-related inquiries troubleshooting issues and facilitating communication between employees and relevant vendors or departments.
  • Collaborating with HR finance and other departments to ensure seamless coordination of payroll and benefits processes with other HR and financial activities.
  • Stay current on ADP payroll system updates and training to ensure the highest return on investment for payroll system.
  • Other activities and tasks assigned by Payroll Director.

Qualifications and Skills

  • Bachelors degree preferred.
  • 5 years of payroll experience.
  • ADP WFN experience is highly preferred.
  • Proficient with Microsoft Office Excel (PIVOT Table V-Lookup SUM IF).
  • Excellent organizational and communication skills.
  • Ability to prioritize workload.
  • Attention to detail.
  • Ability to work in a fast paced ever-changing environment.
  • Versatile and flexible with the ability to work independently on assigned tasks and take directives on given assignments.
  • Knowledgeable in equity payroll processing and reporting requirements (which includes RSU ESPP ISO and NQ).
  • Familiarity with year-end payroll activities including reconciliations and reporting.

Madrigals Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

All employees receive equity which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidates qualifications skills education experience business needs and market demands. The base salary range for this position is $123000 to $151000 per year.

All full-time employees receive equity which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits including flexible paid time off medical dental vision and life/disability insurance and 401(k) offerings (i.e. traditional Roth and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance legal services and other addition we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal state and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications merit and business need. Applicants will receive consideration for employment without regard to race ethnicity color religion sex gender identity sexual orientation national origin age disability protected veteran or disabled status or other characteristic protected by applicable federal state or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals Hiring Managers seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigals name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g. fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses with Madrigal misspelled have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to .

Required Experience:

Manager

Posted 2025-11-20

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