Senior Scientist, Biochemistry
We are seeking a highly motivated and experienced Scientist/Senior Scientist with passion and drive to join our Translational Research team. The successful candidate would provide research support in biochemical and biophysical assay development, and work in partnership with a multi-disciplinary drug-hunting team. The ideal candidate will have deep knowledge and experience in biochemistry, protein science, biophysics, variety of analytical methods, structural biology, and impact in the discovery of novel small molecule modulators for rare disease targets.
Responsibilities · Design, execute, and analyze complex biochemical experiments to support research goals.· Manage projects
· Designing protein constructs for various biophysical assays.
· Be able to design, run, and interpret data from other biophysical techniques such as ITC and NMR.
· Work collaboratively within a matrix team to execute on hit identification using biochemical & biophysical tools.
· Communicate results to cross functional and project teams.
· Maintain up-to-date experimental notebook and other relevant records.
Required Qualifications · PhD in Biochemistry (or related field) or BS with 7+, & MS with 5+ years of relevant small molecule drug discovery experience
· Experience in various enzymatic activity assay development
· Deep understanding and experience with protein engineering/protein science
· Experience in assay optimization and trouble shooting
· Partnering with CROs for timely execution of project deliverables is a plus.
· Good problem-solving skills, capable of finding innovative ways to overcome issues in developing assays with challenging proteins.
· Excellent communication, planning, organizational skills
· Demonstrated flexibility to thrive in a team-oriented, fast paced, technically challenging projects.
Additional Skills/Preferences · Experience in SPR and/or ITC is a plus
· Experience in structural biology is a plus
· Prior research experience in a drug-discovery is preferred Pay Rate Range: $75-100/hr depending on experience
Recommended Jobs
Breast Oncology Opening in Boston - Academic
A leading integrated health system in Massachusetts that brings together the best academic and community healthcare to deliver exceptional, connected, and accessible care is adding a Breast Oncologis…
Mail Carrier
Now Hiring - USPS CDS Rural Mail Carrier TNStumpff Enterprises, LLC, the nation’s leader in Contract Delivery Service for the United States Postal Service, with offices in 20 states, is currently…
Dining-Driver
Job Description Job Description Description: Job Title: Dining Services Staff/Drivers Job Summary: We are seeking reliable and dedicated Dining Services team members to join our team. Th…
AI & GenAI Data Scientist - Manager Save for Later Remove job
At PwC, our people in data and analytics focus on leveraging data to drive insights and make informed business decisions. They utilise advanced analytics techniques to help clients optimise their o…
Venous Access Nurse South Shore Hospital
Overview The Venous Access Nurse's responsibilities include vein assessment, planning, implementation, and evaluation of nursing care for a complex patient population. Provides patient and famil…
SCO Bilingual GSSC (English/Spanish)
Job Description Job Description Job Title: SCO CCA GSSC Bilingual English/Spanish Business Unit: Senior Care Options (SCO) Department: Direct Services Reports to: Program Manager F…
US Business Development Manager
Job Description Job Description Powertech is a cleantech company with the mission of being a trusted innovation partner providing solutions, specialized testing, and technical expertise for a saf…
Restaurant Manager
Job Description Job Description Description: Giana Restaurant is a newly formed presence in the upscale American dining scene, nestled in the heart of Easton. With a relentless commitment to c…
Pediatric Integrated Behavioral Health Clinician (LICSW/Psychologist) - East Falmouth, MA
At LifeStance Health, we believe in a truly healthy society where mental and physical healthcare are unified to make lives better. Our mission is to help people lead healthier, more fulfilling lives …
Associate Mechanical Engineer
Associate Mechanical Engineer Location Lexington, MA : The Mechanical Engineering Group focuses on developing innovative mechanical design solutions for ground, airborne, and spaceborne applications.…