Chromatography Principal Scientist

Sanofi (US)
Cambridge, MA
Job Title: Chromatography Principal Scientist

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

Sanofi is seeking a highly motivated individual to join our analytical group as a Chromatography Principal Scientist . The group is part of the synthetic platform within Global CMC Development with focus on small molecules that is striving to become an industry leader in the development of transformative medicines.

The primary responsibility of this position is to provide analytical support to the chemistry teams and to develop analytical methods mainly on small molecules using equipment including HPLC, UHPLC, GC, and potentiometry.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

  • Develop specific and robust analytical methods using equipment including HPLC, UHPLC, GC, and be responsible for validating the methods when necessary
  • Analyze synthetic molecules mainly by HPLC/UHPLC, GC, potentiometry, and TLC.
  • Perform quantification of impurities
  • Perform mass balance studies
  • Design and implement analytical strategies for synthesis intermediates and raw materials
  • Develop effective collaborations with others within project teams and between analytical groups
  • Generate technical reports independently
  • Share knowledge and experience of analytical method development for synthetic molecules
  • Introduce innovative analytical approaches to facilitate optimal decision-making.
  • May serve as a project lead

About You

Basic Qualifications

  • A Master’s degree or equivalent in Analytical Chemistry or related field with a minimum of 8ears, or a PhD with minimum of 5 years of experience in the pharmaceutical/biotech industry. A PhD in Analytical Chemistry is preferred.
  • Expertise in the operation of LC and GC
  • Familiarity with the operation of potentiometry titrator, and TLC from multiple manufacturers
  • Extensive experiences in method development using HPLC/UPLC and GC
  • Experiences in analytical method validation
  • Record of adhering to and promoting lab safety practices
  • Good communications skills

Preferred Qualifications

  • In-depth understanding of the separation principles of LC, GC and method development software.
  • Deep expertise in chromatography method development and trouble shoots
  • Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission
  • Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team setting
  • Demonstrated project management skills
  • Consistent record of collaboration with scientists and other stakeholders at external enterprises
  • Advanced scientific network in the industry and academia
  • Record of patents and publications

Why Choose Us?
  • Bring the miracles of science to life alongside a supportive, future-focused team.
  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SG
#LI-GZ

#LI-Onsite
#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Posted 2025-09-10

Recommended Jobs

Pharmacy Technician

Tarrytown Expocare LLC
Walpole, MA

Job Description Job Description Description: As a Pharmacy Technician, you will actively label and dispense prescription orders, including providing unit dose packaging (e.g., blister cards). Yo…

View Details
Posted 2025-09-06

CNA

IsentCare
Methuen, MA

(Only QUALIFIED Healthcare Professionals accepted) Nursing Assistant/Certified Nursing Assistant - A Certified Nursing Assistant (CNA) We are currently seeking a Certified Nursing Assistant who is p…

View Details
Posted 2025-08-23

Occupational Therapist (Early Intervention)

Meeting Street
New Bedford, MA

Job Description Job Description Description: Looking for a rewarding career that makes a difference in children’s lives? Look no further and join the team at Meeting Street! Meeting Street is a …

View Details
Posted 2025-07-29

Occupational Therapist - Early Intervention

Kennedy-Donovan Center
Massachusetts

Are you looking for an organization that allows flexibility in your work schedule?! At KDC we are on a mission to empower and support all people to meet their full potential in a world where every …

View Details
Posted 2025-09-02

CDL Driver with S&P

The Guild of St. Agnes
Worcester, MA

Job Description Job Description Job description $1,000 hiring bonus Guaranteed 40HRS of pay! Paid holidays, training days, vacation days and snow days! Monday through Friday routes range i…

View Details
Posted 2025-08-06

Food Service Utility Worker

SGA Talent
Franklin, MA

Food Service Utility Workers Needed in Franklin, MA! Many Shifts Available 20-40 hours per week Company: SGA Lists. A great team to be part of. SGA is a leading hospitality company support…

View Details
Posted 2025-08-28

2nd Class Engineer (CRO)

EthosEnergy
Pittsfield, MA

We are seeking a licensed 2nd Class Engineer, (CRO) to join our team in Pittsfield MA to support the Power Plant with coordination of all on shift operations. Important to note that candidates must…

View Details
Posted 2025-08-27

Math Tutor

Huntington Learning Center of Acton
Acton, MA

Job Description Job Description Job description Looking for part-time tutors who are enthusiastic about their field of mathematics. You must be readily proficient in High School level math inclu…

View Details
Posted 2025-09-01

Full Time Family Practice Job Wellfleet, MA

CompHealth CompHealth
Wellfleet, MA

Whether you are searching for a position in your area or in another state, we have professionals to help you achieve your goals through our relationships with facilities nationwide - in rural settings…

View Details
Posted 2025-09-10

Associate Scientist II

R&D Partners
Cambridge, MA

Job Description Job Description Responsibilities Perform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening o…

View Details
Posted 2025-08-31